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過氧化物酶體增殖物活化受體或稱為脂小體增生活化受體(Peroxisome proliferator-activated ... 其中受体α主要参与肝细胞的氧化过程。受体δ则参与了 ... 替換符號, PPAR.
#2. Peroxisome proliferator-activated receptor (PPAR)-alpha
由 DH van Raalte 著作 · 2004 · 被引用 307 次 — Peroxisome proliferator-activated receptor (PPAR)-alpha is a ligand-activated transcriptional factor that belongs to the family of nuclear receptors.
#3. Peroxisome Proliferator Activated Receptor Alpha - an overview
PPAR -α is a nuclear hormone receptor involved in regulating lipid metabolism and transport, FA oxidation, and glucose homeostasis. ... PPAR-α is predominantly ...
#4. PPAR-α and PPAR-γ activators induce cholesterol removal ...
PPAR -α is highly expressed in liver, heart, muscle, kidney and cells of the arterial wall (such as monocyte-derived macrophages, smooth muscle and endothelial ...
#5. PPARA - Peroxisome proliferator-activated receptor alpha
Peroxisome proliferator-activated receptor alpha · Homo sapiens (Human) · Gene: PPARA (NR1C1, PPAR) · 468 amino acids · Evidence at protein level ...
#6. PPAR-alpha and PPAR-beta expression changes in the ...
Peroxisome proliferator-activated receptors (PPARs, including alpha, beta and gamma subtypes) and their agonists have a protective role in ...
#7. 2P54: a crystal structure of PPAR alpha bound ... - RCSB PDB
a crystal structure of PPAR alpha bound with SRC1 peptide and GW735. ... Substituted 2-[(4-Aminomethyl)phenoxy]-2-methylpropionic Acid PPAR Agonists. 1.
#8. PPAR alpha Antibody (BS-3614R) - Thermo Fisher
PPAR, like several other nuclear hormone receptors, heterodimerizes with retinoid X receptor (RXR) alpha. For Research Use Only. Not for use in diagnostic ...
#9. PPARα Selective Inhibitors | Activators | Agonists | Antagonists
Catalog No Product Name Selective / Pan IC50 / Ki S5121 Phytol Selective S4527 Fenofibric acid Selective S9674 Saroglitazar Selective hPPARα, EC50: 0.65 pM
#10. PPAR-α as a Key Nutritional and Environmental Sensor for ...
One type of PPAR, PPAR-α, is a transcription factor that regulates the metabolism of lipids, carbohydrates, and amino acids and is activated by ...
#11. PPAR-α Modulators as Current and Potential Cancer ...
PPAR -α regulates energy metabolism of lipid, glucose and protein, affects inflammation and eNOS, modulates immune response, and adjusts ...
#12. The Novel Role of PPAR Alpha in the Brain - Springer
Peroxisome proliferator activated receptor alpha (PPAR-α) belongs to the family of ligand-regulated nuclear receptors (PPARs).
#13. PPARA Gene - GeneCards | PPARA Protein | PPARA Antibody
PPARA (Peroxisome Proliferator Activated Receptor Alpha) is a Protein Coding gene. Diseases associated with PPARA include Fatty Liver Disease ...
#14. PPAR Alpha: A Novel Radiation Target in Locally Exposed ...
Peroxisome proliferator-activated receptor alpha (PPAR alpha), a transcriptional regulator of lipid metabolism in heart tissue, has recently ...
#15. Human PPAR alpha /NR1C1 Antibody - R&D Systems
Background: PPAR alpha/NR1C1 ... Peroxisome proliferator activated receptor alpha (PPARA) a member of the steroid hormone receptor superfamily, is a nuclear ...
#16. Rat PPAR-alpha ELISA Kit-NP_005027.2 - MyBioSource
Buy PPAR-alpha elisa kit, Rat PPAR-alpha ELISA Kit-NP_005027.2 (MBS2504779) product datasheet at MyBioSource, ELISA Kits.
#17. PPAR-alpha pathway (Homo sapiens) - WikiPathways
PPAR alpha (also known as NR1C1) is a nuclear receptor that is involved with transcriptional regulation of genes involved in beta-oxidation, ...
#18. PPAR alpha Antibody (600-401-421) | Rockland
Get Rockland's Anti-PPAR alpha (N-terminal specific) (RABBIT) Antibody - 600-401-421 for ELISA, IF, IHC, WB, ChIP. Reacts with Mouse. Order online now!
#19. PPAR-alpha (human) - PhosphoSitePlus
PPAR -alpha Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand ...
#20. Definition of PPAR-alpha antagonist TPST-1120 - NCI Drug ...
PPAR -alpha antagonist TPST-1120. An orally bioavailable, small molecule, selective and competitive antagonist of peroxisome proliferator activated receptor ...
#21. Peroxisome Proliferator–Activated Receptor α Induces ...
In humans, PPAR-α agonists are used for the treatment of dyslipidemia. PPAR-α regulates the expression of genes controlling lipid and lipoprotein metabolism and ...
#22. Anti-PPAR alpha antibody (GTX101098) - GeneTex
Rabbit Polyclonal PPAR alpha antibody. Validated in WB, IHC-P, IP, ChIP assay. Tested in Human, Mouse, Rat, Honeybee, Queen Bee, Plant.
#23. PPAR Alpha | Encyclopedia MDPI
Peroxisome Proliferator-Activated Receptor alpha (PPARα) and Its Role in ... All three PPAR isotypes exhibit potent anti-inflammatory properties and have a ...
#24. PPAR Alpha as a Metabolic Modulator of the Liver - MDPI
Keywords: PPAR alpha; NASH; metabolism; liver; inflammation; gene regulation. 1. Introduction. Among the broad spectrum of nonalcoholic ...
#25. PPAR alpha Transcription Factor Assay Kit (ab133107) - Abcam
Peroxisome proliferator-activated receptors (PPARs) are ligand activated nuclear receptors. Three PPAR subtypes have been identified: alpha, delta and gamma.
#26. Peroxisome proliferator–activated receptor (PPAR)α ...
Peroxisome proliferator–activated receptor (PPAR)α is a nuclear receptor that mediates gender differences in lipid metabolism.
#27. PPAR-α and PPAR-γ agonists for type 2 diabetes - The Lancet
report on SYNCHRONY, a phase II dose-ranging trial of aleglitazar (a dual peroxisome proliferator-activated receptor [PPAR]-α/γ agonist) in ...
#28. Role of PPAR-alpha in Retinal Mitochondrial Function - IOVS
Glucose and lipid are important substrates for retinal ATP production. Peroxisome proliferator-activated receptor alpha (PPARα) is a nuclear receptor regulating ...
#29. PPAR alpha, agonists | DrugBank Online
PPAR alpha, agonists ; Naveglitazar, Naveglitazar has been used in trials studying the treatment of Diabetes Mellitus, Non-Insulin-Dependent.
#30. PPARA / PPAR Alpha - LSBio
PPARA / PPAR Alpha. peroxisome proliferator-activated receptor alpha. Peroxisome proliferators include hypolipidemic drugs, herbicides, ...
#31. PPAR alpha/NR1C1 Antibody (NB600-636) - Novus Biologicals
Cited in 18 publications. View Rabbit Polyclonal anti-PPAR alpha/NR1C1 Antibody (NB600-636). Validated Applications: WB, ChIP, ELISA, Flow, ICC/IF, IHC, ...
#32. Anti-phospho PPAR alpha (Ser73) from rabbit - Sigma-Aldrich
Anti-phospho PPAR alpha (Ser73) from rabbit; Synonyms: Peroxisome proliferator-activated receptor alpha, PPAR-alpha, Nuclear receptor subfamily 1 group C ...
#33. Fenofibrate induced PPAR alpha expression was attenuated ...
Abstract The physiological regulation of Oestrogen receptor α (ERα) and peroxisome proliferator-activated receptor alpha (PPARα) in ...
#34. PPAR-alpha: a novel target in pancreatic cancer - OpenBU
Peroxisome proliferator-activated receptor-alpha (PPARα), a ligand-activated nuclear receptor/transcription factor, is a negative regulator of inflammation.
#35. Metabolomics of the interaction between PPAR-α and age in ...
PDF | Regulation between the fed and fasted states in mammals is partially controlled by peroxisome proliferator-activated receptor-alpha ...
#36. Peroxisome Proliferator-Activated Receptor Alpha (PPAR ...
However, indirect evidence suggests that PPAR-alpha (PPAR-α) may also regulate the vascular supply of endometriotic lesions as well.
#37. PPAR Alpha & Natural Ways to Activate it - SelfHack
PPAR -alpha is mainly found in the liver and brown fat, followed by the heart and kidney. Lower PPAR-alpha expression levels are found in the ...
#38. Molecular mechanism of PPARα action and its impact on ...
Peroxisome proliferator-activated receptor α (PPARα) is a ligand-activated transcription factor belonging, together with PPARγ and PPARβ/δ, ...
#39. The Role of PPAR-alpha during Angiotensin II Hypertension
Peroxisome proliferator-activated receptor (PPAR)-alpha is a nuclear hormone-activated receptor and transcription factor that inhibits, IL-6 production, ...
#40. PPAR alpha Activators | SCBT - Santa Cruz Biotechnology
PRODUCT NAME/Application CAS Cata... ' data‑toggle="tooltip"> ETYA ETYA is a Cox, LO, and PLA2 inhibitor 1191‑85‑1 sc‑2... ' data‑toggle="tooltip"> DRF 2519 DRF 2519 is a dual PPARα/γ agonist sc‑3... ' data‑toggle="tooltip"> GW 9578 GW 9578 is a potent agonist of PPARα 247923‑29‑1 sc‑2...
#41. Peroxisome proliferator-activated receptor-α
Rat, 468, 7q34, Ppara, peroxisome proliferator activated receptor alpha, 26 ... NUC1 | nuclear receptor subfamily 1 group C member 1 | PPARalpha | PPAR ...
#42. The Effect of a Peroxisome Proliferator-activated Receptor ...
The Effect of a Peroxisome Proliferator-activated Receptor (PPAR) Alpha Agonist on Cytochrome P450 (CYP) Monooxygenase Activity in Humans · Hypertension · Drug: ...
#43. 用以治療或預防過氧化體增殖活化受體α(PPAR α)及過 ...
用以治療或預防過氧化體增殖活化受體α(PPAR α)及過氧化體增殖活化受體γ(PPAR γ)媒介之疾病之醫藥組合物.
#44. Peroxisome Proliferator-Activated Receptors—Advances in ...
Shan-Zha (Fruit of Crataegus pinnatifida) is Mainly Related to an Increase of PPAR alpha in Liver of Mice Fed High-Fat Diet. Hormone and Metabolic Research, ...
#45. Array profiling to study PPAR-alpha in progenitor cell - Tebu-bio
Peroxisome proliferator-activated receptor alpha (PPAR-alpha also known as NR1C1) regulates a myriad of biological processes.
#46. PPAR alpha (PPARA) (NM_005036) Human Tagged ORF Clone
PPARA (Myc-DDK-tagged)-Human peroxisome proliferator-activated receptor alpha (PPARA), transcript variant 5.
#47. Dr. Robert Weiss on PPAR-Alpha as a Target in Kidney Cancer
... peroxisome proliferator-activated receptor alpha ( PPAR - alpha ) as a possible new treatment target for patients with renal cell carcinoma.
#48. Anti-phospho PPAR alpha (Ser73) | ABE2888-50UG
Anti-phospho PPAR alpha (Ser73) Anti-phospho PPARalpha (Ser73), Cat. No. ABE2888, is a highly specific rabbit polyclonal antibody that targets Peroxisome ...
#49. Activation of Peroxisome Proliferator-Activated Receptor ...
Peroxisome proliferator-activated receptor alpha (PPARα) is a nuclear ... These PPAR isotypes share high degree of structural homology but ...
#50. PPAR-α, a lipid-sensing transcription factor, regulates blood ...
Lipid sensor peroxisome proliferator-activated receptor alpha (PPAR-α) is the master regulator of lipid metabolism. Dietary release of endogenous free fatty ...
#51. PPAR-alpha DNA-Binding ELISA Kit | Abbexa Ltd
PPAR -alpha DNA-Binding ELISA Kit. Catalogue No: abx596533. Price: £430.00. (Size: 96 tests). Reviews: 0 reviews (0 reviews).
#52. 过氧化物增殖激活受体(PPAR)α 特异性高效多用途抗体
PPARα主要在肝脏、骨骼肌和心脏;PPARγ主要在脂肪组织,肠道和胸部;PPARβ/δ主要在皮肤、骨骼肌等。 PPARa. PPAR-α在调节过氧化物酶体增殖剂基因转录活性 ...
#53. PPAR Signaling Pathway - Creative Diagnostics
Research on PPAR-α is still relatively rare. PPAR signaling pathway. PPAR signaling pathway Cascade. The PPARγ-related signal transduction pathways include the ...
#54. Peroxisome Proliferator-Activated Receptors - Proteopedia
Human PPARγ bound to RXRα and PPRE DNA strand, 3dzy ... The Peroxisome Proliferator-Activated Receptors (PPAR) α, γ, and δ are members of the nuclear ...
#55. Anti PPAR Alpha Antibody | Bio-Rad
Rabbit anti Mouse PPAR alpha antibody recognizes mouse Peroxisome proliferator-activated receptor alpha (PPAR ALPHA), a 52.2 kDa transcription factor ...
#56. PPAR alpha Receptor Agonists: Small Molecules and Peptides
View 6 PPAR alpha Receptor Agonists Small Molecules and Peptides. Bio-Techne offers high-quality reagents instruments, custom manufacturing, and testing ...
#57. Involvement of the peroxisome proliferator-activated receptor ...
Involvement of the peroxisome proliferator-activated receptor (PPAR) alpha in vascular response of endocannabinoids in the bovine ophthalmic artery [2012].
#58. Peroxisome Proliferator—Activated Receptor (PPAR ...
Peroxisome proliferator—activated receptor (PPAR)-α agonists lower circulating lipids, but the consequences for muscle lipid metabolism and insulin ...
#59. PPAR alpha/NR1C1 Rabbit anti-Human, Clone: 2297B, R D ...
Fisher Scientific - Rabbit Monoclonal Antibody Shop PPAR alpha/NR1C1 Rabbit anti-Human, Clone: 2297B, R&D Systems™ at Fishersci.com.
#60. improved pharmaceutical composition containing a ppar ...
WO2003013500 - IMPROVED PHARMACEUTICAL COMPOSITION CONTAINING A PPAR ALPHA AGENT AND A PROCESS FOR PREPARING IT. Publication Number WO/2003/013500.
#61. [PDF] PPAR Alpha Regulation of the Immune Response and ...
PPARs are members of the steroid hormone nuclear receptor superfamily and play an important role in the regulation of lipid metabolism, ...
#62. Synthesis and in vivo evaluations of [11C] KMW01 as a ...
Objectives Peroxisome proliferator-activated receptor (PPAR-α) is a ligand-activated nuclear receptor transcription factor that regulates the fatty acid β- ...
#63. Peroxisome proliferator activated receptor (PPAR)alpha ...
Peroxisome proliferator activated receptor (PPAR)alpha-gamma agonist aleglitazar attenuates tumor necrosis factor(TNF)alpha-mediated inflammation and ...
#64. Sleep profile during fasting in PPAR-alpha knockout mice
Peroxisome proliferator-activated receptor alpha (PPARα) is a transcription factor that belongs to the nuclear receptor family and plays an ...
#65. Activated AMPK inhibits PPAR-α and PPAR-γ transcriptional ...
AMP-activated protein kinase (AMPK) and peroxisome proliferator-activated receptor-α (PPAR-α) are critical regulators of short-term and long-term fatty acid ...
#66. Peroxisome Proliferator-Activated Receptor (PPAR) α/γ 작용제
PPAR α 와 γ 모두를 활성화시키는 이중 작용제(dual agonist). 로 가장 먼저 개발된 약제는 muraglitazar이다. 약제 복용의. 병력이 없는 제2형 당뇨병 환자 1,477명의 환자 ...
#67. 过氧化物酶体增殖物激活受体-α在酒精性肝损伤中的表达
PPAR超家族有3个亚型:即PPAR-α、 PPAR-δ(又称PPAR-β或NUC-1)和PPAR-γ,分别由不同的基因编码.近年来的研究发现,PPAR-α具有调节脂肪代谢、炎症反应、 ...
#68. Peroxisome proliferator-activated receptors-alpha (PPAR-α ...
Peroxisome proliferator-activated receptors-alpha (PPAR-α) and chronic heart failure: Is there a reason to discuss the metabolic strategy of treatment?
#69. Antiserum to-PPAR-Alpha, Purified (Mouse) - Astral Scientific
Antiserum to-PPAR-Alpha, Purified (Mouse) ; Grade: Ultra Pure · $95.00 ; Grade: Biotech Appearance Fine, white homogeneous powder Moisture content ≤10% Gel ...
#70. PPAR alpha Antibody [B4F7] - Cat. No. 15-187 - ProSci Inc
PPAR alpha Monoclonal Antibody can be used for Western Blot,Immunohistochemistry,Immunofluorescence,Flow Cytometry and other antibody applications.
#71. 搜索
[Expression of FXR mRNA, PPAR alpha mRNA and bile acid metabolism related genes in intrahepatic cholestasis of pregnant rats].
#72. The Novel Role of PPAR Alpha in the Brain: Promising Target ...
PDF | Peroxisome proliferator activated receptor alpha (PPAR-α) belongs to the family of ligand-regulated nuclear receptors (PPARs).
#73. Mouse PPARA / PPAR Alpha Protein (Recombinant His-GST)
LS-G24163-100 | Mouse PPARA / PPAR Alpha Protein (Recombinant His-GST) (aa280-433).
#74. Filling gaps in PPAR-alpha signaling through comparative ...
We have focused on PPAR alpha, a ligand-activated transcription factor functioning as fatty acid sensor controlling the gene expression regulation of a ...
#75. PPAR alpha-mediated peroxisome induction compensates ...
... EXPRESSION, Anilides, Animals, Bronchi, Gene Expression Regulation, Mice, Mice, Knockout, Oxidative Stress, PPAR alpha, PPAR gamma, Peroxisomes, ...
#76. Replication Data for: Neuroprotective Effects of PPAR-alpha in ...
Raw data for PLoS One manuscript Neuroprotective Effects of PPAR-alpha in Retinopathy of Type 1 Diabetes.
#77. PPAR agonists as effective adjuvants for COVID-19 vaccines ...
PPAR alpha modulates the transcription of genes involved in beta-oxidative degradation of fatty acids while PPAR gamma acts on glucose ...
#78. Nuclear receptors as never seen before: PPAR ...
PPARs are divided into three isotypes: PPARα, PPARγ and PPARβ/δ, which have different functions. On the one hand, PPAR-α activation reduces ...
#79. 過氧化物酶體增殖物活化受體 - Wikiwand
另外被激活的PPAR-α還可介導載脂蛋白apoA I表達;活化的PPAR-α促進脂蛋白脂肪酶合成,催化脂蛋白中的甘油三酯脂解成游離脂肪酸。另外,有醫藥學方面的研究顯示PPAR-α基因與 ...
#80. Peroxisom-Proliferator-aktivierter Rezeptor - DocCheck Flexikon
PPAR -α: In Leber, Herz sowie Skelettmuskeln exprimiert und fördert die Expression von Enzymen der Fettsäure(β)-Oxidation und der Ketonkörpersynthese. PPAR-δ: ...
#81. Gluten-free diet reduces adiposity, inflammation and insulin ...
Blood lipid profiles, glycaemia, insulin resistance and adipokines were measured. Expression of the PPAR-α and γ, lipoprotein lipase (LPL), hormone sensitive ...
#82. Egy magreceptor, a peroxisoma proliferátor aktivált receptor ...
| PPAR alpha, -beta and -gamma which are transcription factors activated by ligands. Through their lipid ligands environmental effects regulate ...
#83. Nutrición molecular, papel del sistema PPAR ... - SciELO Chile
PPAR isoforms play a central role in lipid homeostasis, regulating anabolic (PPARg) and ... receptor (PPAR) alpha activation and its consequences in humans.
#84. NHR-49/PPAR-α and HLH-30/TFEB promote C. elegans host ...
Infection induces fmo-2/FMO5 via NHR-49/PPAR-α. 149. As the most highly induced infection-specific gene in hlh-30/TFEB mutants (Fig.
#85. Butyrates: Advances in Research and Application: 2011 ...
“This study was designed to investigate the effects of bezafibrate as a PPAR alpha agonist on human embryo rhabdomyosarcoma (RD) cells and possible ...
#86. PPAR[alpha] Enhances Cancer Cell Chemotherapy Sensitivity ...
Consistently, silenced PPAR[alpha] reversed this event. PPAR[alpha]-induced autophagy significantly inhibited tumor growth and enhanced SW480 cancer cell ...
#87. Transforming Growth Factors—Advances in Research and ...
PPAR alpha agonists have been shown to have profound anti-inflammatory and antiproliferative effects on human keratinocytes, and are important for ...
#88. Journal Pre-proof
mTORC2 facilitates liver regeneration through the sphingolipid-induced PPAR-α- fatty acid oxidation. Lingling Zhang, Yanqiu Li, Ying Wang, ...
#89. Peroxisome Proliferator-Activated Receptors—Advances in ...
Interestingly, PPAR alpha-dependent genes responsible for the regulation of bile acid metabolism were down-regulated in the liver ...
#90. Increased, PPAR-alpha activation leads to Decreased, bile flow
Increased, PPAR-alpha activation leads to Decreased, bile flow · Key Event Relationship Overview · Key Event Relationship Description · Evidence Collection ...
#91. The Peroxisomal Proliferator-Activated Receptor (PPAR ... - jstor
Receptor (PPAR) a Agonist, Fenofibrate, Prevents Fraction ... Peroxisome proliferator-activated receptor-{alpha} activation as a.
#92. 什麼是PPAR (Peroxisome Proliferator Activated Receptor
PPAR 的發現,是21世紀醫學健康與長壽的新革命,不但可調控血脂、血糖,還可抗發炎與抑制癌症。 ... 其中受體α主要參與肝細胞的氧化過程。
#93. Therapeutic Effects of PPAR[alpha] on Neuronal Death and ...
Peroxisome-Proliferator Activated Receptor-Alpha (PPAR α ). PPARα is a transcription factor and belongs to the nuclear receptor superfamily [1].
#94. PPAR Alpha Gamma Dual Agonists : What You Need To Know
Prof Sacks, USA reviews the available data about PPAR gamma agonist (Pioglitazone) especially data from the PROACTIVE study published in the ...
#95. PPAR-α contributes to the anti-inflammatory activity of ...
that Peroxisome proliferator activated receptor alpha-α (PPAR-α), an intracellular transcription factor activated by fatty acids, ...
#96. Emerging role of the peroxisome proliferator-activated ...
Abbreviations: PPARγ, peroxisome proliferator-activated receptor γ; PARP, poly(ADP-ribose) polymerase; TNF-α, tumor necrosis factor-α; cdc, ...
#97. PPARγ의 이해 - 청년의생명과학포럼(Young Biomedical ...
PPARs는 alpha, beta, gamma 모두 중요한 역할을 하고 있지만, 이번 칼럼에서는 당뇨병과 관련이 있는 peroxisome proliferator-activated receptor gamma(PPARγ)에 ...
#98. KEGG PATHWAY Database
... 00592 M: alpha-Linolenic acid metabolism; 01040 M N: Biosynthesis ... 07222: Peroxisome proliferator-activated receptor (PPAR) agonists.
ppar alpha 在 Dr. Robert Weiss on PPAR-Alpha as a Target in Kidney Cancer 的推薦與評價
... peroxisome proliferator-activated receptor alpha ( PPAR - alpha ) as a possible new treatment target for patients with renal cell carcinoma. ... <看更多>