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在aspirin effect這個產品中，有9篇Facebook貼文，粉絲數超過1萬的網紅小小藥罐子，也在其Facebook貼文中提到， 【藥事知多D】亞士匹靈 + Dipyridamole = ？ 〈點解有時亞士匹靈有時可能會搭配Dipyridamole呢？〉 有時亞士匹靈(Aspirin)可能會搭配Dipyridamole。 這時候，大家便可能會感到有點奇怪： 「咦？藥罐子，亞士匹靈通血管，我知道，那Dipyridamol...

aspirin effect 在 小小藥罐子 Facebook 的最佳解答

小小藥罐子 By 小小藥罐子

2021-01-13 10:14:36 有 395 人按讚
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【藥事知多D】亞士匹靈 + Dipyridamole = ？

〈點解有時亞士匹靈有時可能會搭配Dipyridamole呢？〉

有時亞士匹靈(Aspirin)可能會搭配Dipyridamole。

這時候，大家便可能會感到有點奇怪：

「咦？藥罐子，亞士匹靈通血管，我知道，那Dipyridamole又是什麼？」

哦，跟亞士匹靈一樣，Dipyridamole其實同樣是一種抗血小板藥(Antiplatelet)，在藥理上，是一種磷酸二酯酶抑制劑(Phosphodiesterase Inhibitor)，主要抑制磷酸二酯酶(Phosphodiesterase)，從而提高血小板裡面環腺苷單磷酸(Cyclic Adenosine Monophosphate, cAMP)、環鳥嘌呤苷單磷酸(Cyclic Guanosine Monophosphate, cGMP)的水平，從而抑制血小板凝聚，產生「通血管」的效果。

好，問題是，為什麼會刻意一同使用這兩種藥呢？

哦，理論上，同時使用兩種不同作用原理的抗血小板藥，兩路夾擊，便能夠產生「協同效應(Synergic Effect)」，增加「通血管」的功效。

實際上，相較單一使用亞士匹靈、Dipyridamole而言，雙劍合璧能夠加強預防中風的功效。[1]

不過有利自然有弊。

不難想像，藥物愈多，副作用自然愈多。首先同服兩種抗血小板藥，不用問，自然便可能會矯枉過正，反而增加出血的風險。

除此之外，因為Dipyridamole還能夠阻斷腺苷(Adenosine)這種血管擴張劑(Vasodilator)在紅血球的再回收，從而增加血液的腺苷水平，固然能夠舒張血管，同時還可能會舒張體內其他不同的血管，例如頭顱，從而誘發頭痛。

所以一般建議睡前服用，同時還可以採取漸進式加藥，在兩、三天內逐步增加劑量，目的在給予時間讓身體能夠慢慢適應，從而希望能夠減輕頭痛的副作用，不過這種頭痛一般會隨著身體慢慢適應而逐漸消失。[2]

（如欲了解更多用藥資訊，歡迎看看「小小藥罐子」網誌。）

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Reference:
1. Diener HC, Cunha L, Forbes C, et al. European Stroke Prevention Study 2: Dipyridamole and acetylsalicylic acid in the secondary prevention of stroke. J Neurol Sci. 1996;143:1-13.
2. Theis JG, Deichsel G, Marshall S. Rapid development of tolerance to dipyridamole-associated headaches. Br J Clin Pharm. 1999;48:750-755.

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本網誌旨在分享用藥知識，圖文僅供教育用途。 內容僅供參考，絕對不能用來自行診治。 本網誌致力確保內容準確，惟醫藥知識隨時更新，故對內容的準確性、完整性、及時性、適用性不會承擔任何責任。如有健康疑難，請盡快求醫，以免貽誤治療良機。部分內容涉及醫藥知識，可能會引起不安，敬請留意。
一個小小的藥劑師， 一個小小的用藥資訊平台。 著作：《藥事知多D》、《用藥知多D》、《藥房事件簿》、《家居藥物攻略》
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aspirin effect 在 當張仲景遇上史丹佛 Facebook 的最讚貼文

當張仲景遇上史丹佛 By 當張仲景遇上史丹佛

2020-10-08 12:22:40 有 340 人按讚
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川普的新冠治療

美國川普總統感染新冠肺炎，住院短短三天後出院，雖然川普總統的「出院」離「痊癒」還有一大段距離，這樣快速的進展讓很多醫學人士及一般大眾非常好奇，紛紛討論這位歐美國家中最有權力的人物，到底是接受了怎麼樣的治療方法。

依據各種新聞報導及醫學評論，以及我和幾位西醫專家的討論，簡單來說，川普總統接受了三個步驟的治療。第一個步驟是Regeneron製藥公司的「多株抗體雞尾酒療法 REGN-COV2」，讓病人體內的抗體數目大幅增加，期待抗體和病毒RNA結合，阻止或減緩病毒RNA竊取人體細胞而大量複製，減少體內病毒的數量，並改善病人症狀。第二個步驟是使用Gilead製藥公司的「瑞德西偉 Remdesivir」，期待減緩新冠病毒複製，縮短病人康復時間。第三個步驟是使用皮質類固醇「地塞米松 Dexamethasone」，人體免疫系統盲目混亂地抵抗病毒時，造成體內大規模的發炎現象，可能嚴重損傷人體器官，「地塞米松 」是用來治療關節炎及其它免疫系統疾病的消炎藥。另外，根據白宮新聞公告，川普總統還服用了阿斯匹靈 Aspirin、抗組織胺及制酸藥 Famotidine、褪黑素 Melatonin、維他命Ｄ、鋅補充劑等等。

如果這樣的治療方式有效，為什麼不拿來治療所有的新冠肺炎確診病人？問題沒有那麼單純，除了主要藥物的價格不菲外，那些藥物都是特殊性質、一刀兩刃的藥物，使用的時機、先後順序、劑量等等都非常關鍵，稍有偏差，不但沒法逆轉病情，可能還會導致更嚴重的問題。因此，即使川普總統真的因此而痊癒，也不代表可以大規模地使用在幾十萬、幾百萬個確診病患身上。

另外，川普總統的治療突顯出西醫學及西藥研發的巨大困境。很多人認為西醫「明明白白」、中醫「模糊不清」，總以為西藥的作用有很清楚的病理及生物化學解釋，「A造成B，B造成C，把病因阻隔了，病情就控制了」，其實，這樣的認知往往是錯誤的。美國食品藥物管理局（FDA）藥物申請過程，以「安全性」及「有效性」為考核標準，「安全性」不太需要解釋，讀者大概都知道是什麼意思，重點在於「有效性」是如何建立了。

西藥研發的過程中，當然得對疾病的原因有基本的認識，也對治療方法有些概念，不能隨便亂猜，不然龐大的研發經費將付諸流水。但是，理論歸理論，「有效性」的考核不在於醫理的解釋，而是臨床試驗的結果。換句話說，FDA並不在乎你的理論有多合理、多深入，只要你的臨床試驗效果超過現有的醫療方法及安慰劑作用（placebo effect），「安全性」又在權衡下的合理範圍內，你的藥物就被核准上市。另一方面，這二三十年來，西藥研發的費用攀升了十倍、百倍，「簡單疾病」的西藥也早被各個西藥廠給掌控了，新西藥的研發變得非常困難。怎麼辦？最直接的辦法就是拿現成的「舊藥」來試一試各種「新問題」，「安全性」的評估在當初「舊藥」研發時就已經通過FDA審核，現在只需要找些病人來臨床試驗「新問題」。如果運氣好，臨床試驗顯示出一些效果，那又是幾百億、幾千億美金的市場，如果運氣不好，臨床試驗沒有什麼效果，經費損失遠小於動輒幾十億美金的新藥研發。至於，這些「舊藥」治療「新問題」的理論基礎、生物化學的來龍去脈，只要能通過FDA的臨床試驗，沒有多少人會關心，更不用說實際治療大量病人的效果及尚未察覺的副作用，那可能要等到十年後出了問題，才會有人拿出來討論。

這樣的「Trial and Error （反覆試驗改錯)」，正是歐美國家應付新冠肺炎的方法，而川普總統的治療是其中最被大家關注的試驗。不過，事情總有兩面，這樣各種西藥治療新冠肺炎的臨床試驗，其實也適用於中藥方劑的審核。「大青龍湯」、「射干麻黃湯」等中藥方劑內的各個中藥材早就被FDA准許使用，很容易通過「安全性」的審核，然後再找個幾十位新冠確診病人來做中藥方劑的「雙盲測試」，只要效果在某個程度以上，FDA一樣會准許上市，是不需要解釋為什麼這麼一堆花花草草可以治療新冠肺炎的！很可惜，「雙盲測試」的費用對大西藥廠來說沒什麼，對中醫師、中醫診所而言，卻是一筆龐大的經費，沒有投資基金或政府機構的支持，是很難付出實踐的。

這裡再提一個插曲。上週我和心臟內科醫生見面討論，心臟內科醫生很感慨地說，西醫臨床治療比一般人想像的混亂很多。他以血液凝結為例子，心臟內科醫學有好幾個驗血指標來判斷病人血液凝結的可能性及速度，卻沒有一個指標真的「準」，心臟外科醫生根本不看這些指標。那麼，心臟外科醫生開刀時怎麼做決定？很簡單，病人麻醉後，直接在病人身上劃一刀，看看多少秒內可以凝血，最實際也最可靠！我問心臟內科醫生那些凝血指標怎麼來的，他說某位醫學專家做了某個研究、發表了某篇論文，然後大家就直接把論文的結論應用到臨床治療，西藥研發也以提高或壓低論文中的「指標」為目標。直到某一天，另外一位醫學專家做了某個研究、發表了某篇論文，推翻了原來的理論，大家才轉向，換成以新的「指標」來治病。更麻煩的是，許多情況下，一部份的人相信舊的理論，一部份的人相信新的理論，學術界因而產生了不同的學派，臨床醫生也因而採取差異很大的治療方法。各說各話，就好像美國心臟科學會幾年前把高血壓標準放鬆，認為血壓會隨著年紀增長而自然提高，六十歲以上的人血壓150，不是什麼太大的問題。結果，不到兩年，心臟科學會高層改選後，立即把高血壓標準大幅壓低，不但不承認血壓隨著年紀增長而提高為正常的，反而把正常血壓標準訂的比幾年前更低，當然，馬上也就有更多病人被醫生要求長期服用高血壓藥物！

（http://andylee.pro/wp/?p=8846）
#當張仲景遇上史丹佛

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當張仲景遇上史丹佛

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關於部落格 我本來是個科技人，也是一個科技管理與投資人，受過現代化邏輯分析訓練，從量子物理的嚴密數學推衍，無線通訊軟硬體的系統設計，到複雜的公司購併與投資財務模型，無一不是嚴格的「科學分析」與「實事求是」。換句話說，我本來跟中醫一點關係都沒有， 也跟很多不了解中醫的人一樣，覺得中醫很不科學，甚至覺得中醫已經該被淘汰了。 我為什麼會走到中醫的領域呢？十年前左右，正當我頂著史丹佛電機博士及柏克萊MBA的光環在矽谷汲汲營營時，我父親得到了肝癌。一開始醫生說仍不嚴重，只有1.2公分，栓塞手術即可去掉腫瘤。第一次栓塞後，果然腫瘤迅速縮小，可是不到三個月，新的肝腫瘤冒出來，竟然有5～6公分。又再次栓塞，第二顆腫瘤也縮小，然而，又不到三個月，再度有新的肝腫瘤冒出來，這一次成為11公分，連醫生都不相信腫瘤可以長得這麼快，只能說那叫做「多發性肝癌」。 我一方面不能理解這樣的病情發展及醫療方式，另一方面想幫助父親，我開始作研究，查詢各種資料，請教各類醫學專家。很快的，我了解到現代西醫學對慢性病的處理是很有限的，就連美國疾病管理中心 (Centers of Disease Control and Preventions, CDC)，美國國家衛生研究院(National Institute of Health, NIH)， 世界衛生組織 (World Health Organization, WHO) ，以及很多其它世界頂尖醫學研究組織都表示，現代西醫學沒有辦法有效治療癌症，心血管疾病，關節炎，失眠，憂鬱症，體重過重等等慢性疾病，標準醫療程序有很多的爭議及副作用。這讓我很驚訝，深入了解後才明瞭，現代西醫學在分子生物學層面上，或許很科學，但是在臨床治療，並非我以前認為那般邏輯化，而且臨床治療往往非常局部化，缺乏整體理論與模型，而是以嘗試錯誤 (trial and error)及鬆散的統計數據為主。以一個科技人的背景而言，這樣的一門學問，似乎達不到「科學」的條件。同時，我發現，和我有相同想法與疑問的人其實很多，甚至有好幾位史丹佛大學的西醫專家教授，當面指出西醫臨床上的缺失，並大聲質疑西醫學上的很多問題。 就在我對現代西醫學感到無助時，有朋友及西醫專家要我去多了解中醫，這些人都有見證過或親身經歷過中醫治療的效果 。我一開始時，無法接受這樣的建議，就連現代西醫學都達不到嚴謹的科學標準，古老的中醫又如何能提供一條大道呢？然而，人的緣分是很難解釋的，在這個時間點上，我碰上了中醫經方派大師倪海廈中醫師。倪先生病人案例讓我很驚訝，我保持科技人懷疑的精神，去了解去查驗。我慢慢的對中醫有了很不一樣的認識，開始愛上中醫，而倪先生也成為我中醫的啟蒙老師，帶領我進入了中醫的世界，我從一個不懂中醫的人，轉變成一個中醫的支持者與實踐者，經過很多很多的臨床驗證，我實在不得不讚歎古老中醫的偉大。 中醫其實是一門很嚴謹的科學，非常俱有邏輯性，臨床效果往往超過一般人的想像。然而，很多人對中醫有很多的誤解，更有很多人利用中醫的名號做不肖的生意，讓中醫背負了很多的罪名。所以，我想寫個部落格，來說明我所認識的中醫，這當然無法闡述整個中醫學問，更無法代表整個中醫界對中醫的看法。然而，希望藉由我嚴謹的科學與科技背景，以及我在臨床上做到很多人認為中醫無法做到的病例，來喚醒一般人對中醫的誤解與懷疑。 以現代科學方法來闡述中醫，至少有兩條路。第一條路是用現代的醫學、生命科學、分子生物學等等來說明中醫古書中的理論及治療方法。很多人試著使用這個方法來解釋中醫，我也曾花費不少心思與力氣在這條路上。然而，我認為這樣的方法雖然有其一定的價值，它可能不是最好的方法，這種使用一門學問去解釋另一門渾然不同學問的方法，就好像硬要用化學的化學反應去解釋物理學的萬有引力，看起來都是在解釋自然現象，兩者的出發點和基本定律(axioms)完全不同，即使在最終的理論上或許可以聯結，但在實際生活應用上不是很有效率的 。 另一條以現代科學方法來闡述中醫的路，是利用基本科學的精神，以及邏輯推理的方法，把中醫當作完全獨立的學問，先不要想證明中醫的基本定律，而是想辦法從那些基本定律推衍，看看是否能在人體現象與治病上得到相符合的結果，如果在多次應用上得到很好的相符性，那麼這些中醫基本定律就有很高的科學價值。也就是說，我們先不要急著用現代醫學來解釋中醫古書中的理論，我們把中醫古書中的基本定律條列整理出來，利用邏輯推理，應用在臨床治療上，看看人體的反應及治療效果是不是和我們推理預測的相符合，如果符合性很高，那這些經典中的基本定律就值得我們尊敬與接受，即使我們不能解釋這些基本定律，那只代表「現代醫學」這項「工具」還不夠先進，畢竟「現代物理學」不能解釋的自然現象也仍然太多太多。 至於部落格為何取名為「當張仲景遇上史丹佛」，這得提到一本書「當孔子遇上哈佛 」。前輩元大創投董事長李克明先生是哈佛大學嚴格訓練出來的法學博士及企業管理碩士（MBA），是位專精跨國商務及企業購併的國際律師，更是國際金融企業的頂級專業經理人，經歷過無數次的商場鬥智。 十年前，李董事長因緣際會重新拾起論語孟子等等中國經典，他驚然發現，他幾十年來累積無數的商場心得與智慧，竟然早在幾千年前就被古人討論過，而這些經典書籍裡的智慧更遠遠超過他的想像，於是李董事長以他哈佛企管與法律所貫輸的邏輯思維 ，全心投入中國經典研究，也因此寫了「當孔子遇上哈佛」。當我向李董事長請益時，了解到我個人從西方教育轉向中國古老智慧的歷程與李董事長頗為相似，一個講治人心，一個講治人體，而我寫這部落格時，也受到李董事長的大力鼓勵。因此，我也就沿著李董事長的書名，把孔子換成中醫醫聖張仲景，把哈佛換成我的母校史丹佛，成了「當張仲景遇上史丹佛」。
當「中醫醫聖張仲景的經典學說」遇上「現代大學史丹佛的科學思維」 (www.D
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aspirin effect 在 Pakar diari hati Facebook 的最佳解答

Pakar diari hati By Pakar diari hati

2020-05-18 08:00:42 有 706 人按讚
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Kanak kanak 3 tahun terpaksa makan ubat jantung orang dewasa.

PENYAKIT ‘KAWASAKI’ MUNGKIN MENINGKAT AKIBAT COVID 19 - pakar perubatan

‘KAWASAKI DISEASE TIDAK BERODA TIDAK BERENJIN’

Kawasaki disease ni adalah antara kids specified illness yang berpotensi menyebabkan komplikasi jantung.

So once dah kena, kemungkinan besar nak ambik insurance, tak lepas.

Please please please protect you kid NOW. BE PREPARED.

Penyakit Kawasaki adalah penyakit peradangan yang dapat menimbulkan komplikasi jangka panjang pada jantung.
Penyakit yang sering dialami oleh anak di bawah usia 5 tahun ini awalnya menyerang mulut, kulit, dan kelenjar getah bening.

Kawasaki disease ni adalah penyakit berkaitan dengan salur darah.
Keradangan salur darah dan komplikasi yang perlu diberi perhatian ialah pada saluran jantung (coronary vessel).

Memandangkan ramai yang dok tanya condition Umar El Fateh. So kita share sikit pengalaman 2 kupang pasal Kawaski Disease ni.

29/4/2020
Badan Umar tiba tiba panas masa bangun sahur. So memang bagi ubat demam biasa ja dulu kat dia and monitor sendiri kat rumah. Tapi dah malam nampak dia makin lembik n temperature pun makin tinggi. Tapi kita hold lagi sampai esok

30/4/2020
Pagi time sahur pun badan dia still panas. 39.6. Dia punya panas sampai dah tuam dgn kain basah pun tak sampai 5 minit kain tu dah kering. So pagi2 terus bawak dia pergi klinik. Doctor check kata tonsil dia bengkak. Then doctor terus start dgn antibiotik sbb temperature dia tak turun turun even dah makan ubat

1/5/2020
Time sahur dia dah bangun sebab badan terlampau panas. 39.8 even dah start antibiotik. Then time tu baru perasan mcm ada beguk dekat telinga belah kanan dia. Umar nampak makin lembik. Start muntah muntah juga. Harini public holiday. So nak refer balik kat klinik tapi tutup. So kita mmg terus bawak pergi emergency. Doctor mmg advice suruh admit terus. Doctor pun at first ckp viral fever. Tp sebab nak bg cepat sikit temperature turun dia nak suruh drip terus. N doctor nak buat ultrasound utk make sure bengkak yg mcm beguk tu bengkak biasa or disebabkan ada nanah. Alhamdulillah result ultrasound just mention tu kelenjar biasa takda apa apa yg bahaya. Oh lagi satu Umar mmg tak makan apa apa langsung since dia sakit. LANGSUNG. So mmg perlukan air utk nak make sure dia tak dehydrated. So Umar pun admit la untuk drip n start antibiotic hari ni.

2/5/2020 - 4/5/2020
Start time ni mmg dah tak sedap hati. Tgk condition Umar makin weak compare to semalam. Patutnya dah start antibiotic dia makin okay. Tapi doctor still kata tak apa. Dia nak monitor dulu. Sampai la dah hari ke lima antibiotic pun Umar still lemah. Muka makin sembab. Mata nampak merah. Tangan kaki bengkak. Dia langsung tak berdiri or jalan sepanjang tempoh ni. Mmg tidur, berdukung ja. Muntah muntah. Cirit semua ada. Time ni mmg tak sedap hati dah. Asal doctor datang visit ja mmg complain kata kenapa Umar macam makin lembik? Time ni doctor pun dah nampak pelik n dia mula perasan symptom2 Kawasaki ni ada dekat Umar. Dia bagi satu malam lg if esok still demam juga nak kena ambil darah untuk check.

Time ni la baru nak tanya Maha Guru Google Al- Duniawi research tengok apa tu Kawasaki disease ni sebab tak pernah dengar. Bila baca Ya Allah tuhan ja tau perasaan mcm mana.

5/5/2020
Umar still demam panas malam tu. So subuh2 nurse dah suruh bawak dia pergi treatment room untuk ambil darah. Pagi tu doctor datang bgtau result darah Umar kuman tinggi n ada ciri-ciri Kawasaki. Then doctor terus bawa Umar pergi scan jantung (Echocardiography).
Ada bad news sikit sebab Arteri jantung Umar belah kanan dengan kiri memang ada bengkak n ada air bertakung sikit. Lepas pada scan jantung baru doctor inform yang Umar confirm Kawasaki disease. So bila confirm kena penyakit Kawasaki ni memang kena buat rawatan cepat. Kalau lambat jantung akan bengkak teruk dan akan ada kesan untuk jangka panjang pada pesakit.

Untuk pengatahuan, Kawasaki disease ni dia tak ada test khas macam kita buat ujian saringan covid-19 tu. Untuk confirmkan penyakit Kawasaki ni kena ambil masa yang lama jugak sebab nak kena tengok keadaan pesakit by simptom. Dah ada simptom2 Kawasaki pada pesakit baru buat scan jantung (Echocardiography) then dah dapat result scan baru boleh confirm kena penyakit Kawasaki ka tak. Macam Umar demam dah lebih pada 5 hari baru simptom Kawasaki ni nampak dekat badan dia. So memang kena buat treatment cepat.

Doctor terus suruh proceed treatment. Untuk treatment Kawasaki disease ni kena ambil ubat IVIG. Tapi doctor bagitau siap-siap ubat ni harga dia boleh tahan. Dia kirakan dose Umar nak kena ambil untuk treatment. 9 bottles drip dia kena ambil. Total cost untuk ubat dia je almost RM8k 😱. Ubat ja belum masuk benda-benda lain lagi.
Tapi memang tak fikir apa dah. Sbb doctor bgtau kita kena cepat start treatment sebelum makin melarat. So start 1:50pm Umar on drip for 12hrs non stop. Since Umar warded 3 kali dia kena tukar branula sebab tangan dia makin lama makin bengkak so drip tak jalan.

6/5/2020
Alhamdulillah Umar settle 9 bottle drip tu by 3 pagi juga. Lepas pda tu mmg Umar takda demam dah. Alhamdulillah. Muka dia pun nampak lagi ceria n tak sembab mcm sebelum ni. YaAllah lega rasa masa ni. Dia dah boleh senyum n respond bila kita cakap dengan dia. Alhamdulillah. Tapi dalam tengahari nurse check temperature dia still ada mild fever. Allah risaunya masa ni. Sampai malam pun range temperature dia still border range. So doctor nak monitor dia lagi

7/5/2020
Kalau ikutkan plan awal, harini dah boleh discharge. Tapi sebabkan Umar still tak sihat ada demam, doctor tahan lagi 1 malam. Nak monitor sampai dia takda demam langsung baru boleh bagi balik. Alhamdulillah Umar active the whole day.
Ok mai nak share sikit pasal ubat dia. Lepas pada treatment Umar kena makan ubat Aspirin. Doctor kata mmg org yg ada masalah jantung akan makan ubat ni. Tapiiiiiiiiiii even org besar yang ada masalah jantung akan makan ubat ni SEHARI SEKALI. Tapi Umar skrng kena makan ubat ni TIGA KALI SEHARI. Dose yang sama ya. Sedih sangat bila tengok dia terpaksa depend dengan ubat yg kuat mcm ni sekali 😔

8/5/2020
Alhamdulillah Umar dah 95% recover. Dah boleh discharge today. Now tangan Umar start menggelupas terkeluar habis kulit tangan dia. Maybe effect ubat or mmg symptom kawasaki ni juga. 8 hari berkampung yang penuh dengan cabaran. Alhamdulillah manage to survive. Syukur kepada Allah 🤲🏻🙏🏻. Thank you family yang banyak membantu n terima kasih banyak untuk yg mendoakan Umar Fateh. Terima kasih juga kepada Dr Tan dari Avisena. Antara Dr yang tersempoi. Dia boleh mai check patient bawak pam dengan ballon untuk bg dekat budak-budak. Siap buat bentuk macam-macam lagi. Thanks Dr Tan 🙏🏻.

P/s : Total bill hospital Umar RM17k++.
Kepada Ibu Bapa diluar sana sedialah payung sebelum hujan. Kalau mampu ambil lah insurans takaful untuk anak-anak. Malas dah nak terang sebab apa kena ambil. Sekarang dah 2020.

So ini la serba sedikit experience n journey yang sy dah lalui untuk share dengan semua pasal Kawasaki disease ni. Saja share bukan sebab sy agent insurance ka apa tapi sebab this time kita rasa berbaloi sangat dengan monthly fee yg tak seberapa tu boleh tolong kita time time mcm ni. Lately dah start nampak case Kawasaki ni tengah naik jugak musim2 covid19 ni. So please stay safe dan doa banyak-banyak. ❤️😇

https://www.facebook.com/1000009625469…/…/3918794224829290/…

https://thediagnosa.com/penyakit-kawasaki-punca-simptom-ra…/

Bukan kes saya, bukan anak saya.

sharing dari kenalan yang anak dia dijangkiti ‘
‘kawasaki’
Sumber/credit : Abdul Basit M Ariff

Kredit : @nur leayanna juan

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Disebalik nama pena Pakar Diari Hati (PDH), nama diberi diberi mama dan ayah ialah Aidil Sahipaludin. Passion saya menulis, diari ini catatan peribadi saya untuk inspirasi, peringatan, pengajaran, hiburan dan ilmu dikongsi bersama. Doakan jodoh, rezeki, dan kebaikan berpanjangan agar tulisan-tulisan ini terus hidup bersama kalian.
Laman perkongsian rasmi Pakar Diari Hati (PDH). Saya menulis dengan hati agar dapat menyentuh hati-hati yang membacanya - Guru, Penulis & Motivator.
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社群媒體上有些相關的討論：

aspirin effect 在 Aspirin and Prostaglandins - YouTube 的推薦與評價

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Aspirin is a medicine used to treat many conditions that cause pain, fever, or inflammation. It's also sometimes taken to treat or prevent ...

#29. ASPIRIN | Drug | BNF content published by NICE

Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for ASPIRIN.

#30. Durlaza (Aspirin) Oral: Uses, Side Effects, Dosages - Verywell ...

Durlaza (aspirin) is a prescription NSAID that lowers the risk of a stroke, heart attack, or death in patients with a history of these ...

#31. aspirin | Description, Uses, & Side Effects | Britannica

Aspirin, derivative of salicylic acid that is a mild nonnarcotic analgesic useful in the relief of headache and muscle and joint aches. Aspirin is effective ...

#32. aspirin and caffeine | Michigan Medicine

It works by reducing substances in the body that cause pain, fever, and inflammation. Caffeine is used in this product to increase the pain relieving effects of ...

#33. Aspirin overdose Information | Mount Sinai - New York

Learn about Aspirin overdose or find a doctor at Mount Sinai Health System. ... Acetylsalicylic acid overdose ... Much lower levels can affect children.

#34. Aspirin: Basics, Side Effects & Reviews - GoodRx

What are the side effects of aspirin? · Stomach bleeding: Vomit that looks like coffee grounds or has blood in it, stools that are bloody or black and sticky ...

#35. Aspirin - Drug Information - Kaiser Permanente

Aspirin. Drug Information. Aspirin is a drug that reduces swelling, pain , and fever. In recent years, long-term low-dose aspirin ... Reduce Side Effects.

#36. Here Are the Health Benefits and Side Effects of Aspirin | Time

But with liver cancer in particular, there is a fine line between enough aspirin for its anti-inflammatory benefit, and the side effect of ...

#37. The Chemistry of Aspirin | The International Aspirin Foundation

The Chemistry of Aspirin (acetylsalicylic acid) ... This in turn mediates aspirin's effect of reduced inflammation and pain in affected tissues.

#38. Aspirin and Heart Disease

The American Heart Association explains the benefits and risks of aspirin therapy to help prevent heart attacks for heart disease patients.

#39. Aspirin Use to Prevent 1st Heart Attack or Stroke Should Be ...

Adults at high risk for cardiovascular disease may face serious side effects if they start a daily regimen of low-dose aspirin.

#40. Dispersible Aspirin Tablets 75mg - Summary of Product ... - eMC

The risk of hypoglycaemic effect with sulfonylureas and insulins may be potentiated with Dispersible Aspirin 75 mg Tablets taken at over dosage (see section 4.5) ...

#41. Low-dose aspirin was associated with an increased risk of ...

The beneficial effects of low-dose aspirin treatment for secondary prevention of CVE in people who already have cardiovascular disease (CVD) ...

#42. How Aspirin Works in Your Body - Ecotrin

Aspirin and other NSAIDs are widely used to address these nerve signals chemically by blocking the effects of certain enzymes that create prostaglandins.

#43. The Aspirin Effect: Pain Relief and More

The Aspirin Effect: Pain Relief and More. ChemSumer. But before you settle into channel surfing, think about that bottle of aspirin or ibuprofen.

#44. Aspirin: Indication, Dosage, Side Effect, Precaution - MIMS

This information is not country-specific. Please refer to the Malaysia prescribing information. Generic Medicine Info. Indications and Dosage. Oral Acute ...

#45. Effect of low-dose aspirin on mortality and viral duration o...

Aspirin (acetylsalicylic acid), a popular medicine, exhibits a variety of effects including alleviating inflammatory response, reducing fever ...

#46. Aspirin vs Aleve | Uses, Side Effects, Dosage and Ingredients

Aspirin (acetylsalicylic acid) and Aleve (naproxen sodium) are nonsteroidal anti-inflammatory drugs (NSAIDs) that reduce pain, fever and inflammation.

#47. All About Aspirin & Its History | Bayer

In fact, Aspirin™ is included in the World Health Organization's list of essential medications based on its pain relief and anti-platelet effects. 1.

#48. Can You Take Aspirin and Ibuprofen Together? - Healthline

Both aspirin and ibuprofen belong to a drug class called nonsteroidal anti-inflammatory drugs (NSAIDs). They have similar side effects, and taking them together ...

#49. Benefits and Risks of Daily Aspirin Use - US Pharmacist

The agency then stresses that aspirin is a drug and, as such, carries a risk of adverse effects and drug interactions.

#50. Aspirin Use to Prevent Cardiovascular Disease and Colorectal ...

Aspirin's anticlotting effect is useful for primary and secondary CVD prevention because it potentially decreases the accumulation of blood ...

#51. Aspirin: Making Sense of Changing Guidelines

Throughout the 2021 USPSTF statement on aspirin for primary prevention, the main side effect worry is “major bleeding.” For the Task Force, ...

#52. Ask About Aspirin - Preeclampsia Foundation

Low dose aspirin my delay or prevent the onset of preeclampsia. ... "The long-term effect of aspirin usage during preeclamptic pregnancies is actually one ...

#53. Aspirin Sensitivity & Desensitization: What is it, Treatment

Aspirin desensitization can help you tolerate aspirin. ... Some people stop taking aspirin because of these side effects.

#54. Aspirin and the heart - Drug cabinet | BHF

People with cardiovascular disease may be prescribed aspirin to help prevent blood clots. Watch our animation on how aspirin works, possible side effects ...

#55. Aspirin to prevent blood clots (Danamep, Nu-Seals) - Patient.info

Aspirin can be used to prevent blood clots. This leaflet discusses what aspirin is, how aspirin can help and the side effects of using ...

#56. Aspirin® Effect – das Granulat für unterwegs

Als Folge der Hemmung sinkt die Erregbarkeit der Schmerzrezeptoren und Schmerzen sowie Entzündungen lassen nach. Aspirin® Effect zählt somit zu den ...

#57. Daily Aspirin Therapy: The Benefits And Risks - Henry Ford ...

Low-dose aspirin can have serious unwanted effects. Aspirin thins the blood (that's how it prevents blood clots), so it's no surprise that ...

#58. No Effect of 5-Day Treatment with Acetylsalicylic Acid (Aspirin ...

Background: The characterization of an individual's hypothalamic-pituitary-adrenal axis stress response is a main research topic in ...

#59. aspirin [TUSOM | Pharmwiki] - TMedWeb

Low doses of aspirin selectively inhibit COX-1. The effect on platelet COX-1 activity is permanent for the lifetime of the platelet, ...

#60. Low-dose aspirin has limited benefits in adults without heart ...

Decades of research has shown the benefits of aspirin to reduce the ... What is the effect of aspirin discontinuation on CVD, mortality, ...

#61. Aspirin and Prostaglandins - YouTube

Therefore, aspirin's effect lasts however long it takes for the cell to transcribe and translate new COX-1 enzymes, which usually takes a ...

#62. The antiplatelet effect of aspirin is reduced by proton pump ...

Objective To evaluate the effect of proton pump inhibitors (PPIs) on the platelet response to aspirin in patients with coronary artery disease (CAD). · Design ...

#63. Aspirin: The Mechanism of Action Revisited in the Context of ...

Aspirin is one of the most frequently used and cheapest drugs in medicine. ... explain the repertoire of anti-inflammatory effects of aspirin.

#64. Enteric-coated aspirin and risk of gastrointestinal effects | IJGM

Aspirin is a medicine to deal with ache and inflammation, but due to its antiplatelet properties, it has evolved into a drug mainly used to ...

#65. Aspirin and Related Drugs - UW Orthopaedics and Sports ...

The salicylates are a family of related drugs that reduce the effects of inflammation, a reaction of the body that causes pain, swelling, redness, and heat. The ...

#66. Aspirin - Uses, Side Effects, Interactions - MedBroadcast.com

Aspirin : Acetylsalicylic acid (ASA) belongs to the group of medications called analgesics (pain relievers), antipyretics (fever reducers), ...

#67. Chemical Properties of Aspirin and its Effect on the Body

Aspirin is FDA approved to reduce fever and inflammation and relieve pain. Though not the most powerful pain reliever available, it is effective ...

#68. Aspirin 500 mg Tablets - Learn Uses, Side Effects & More | Aspiri

Learn about the product and download drug facts and side effects. ... One of the most widely used medicines in the world; aspirin (acetylsalicylic acid).

#69. Effects of Low-Dose Aspirin on Acute Inflammatory Responses ...

An equivalent treatment regimen with salicylate had no effect on TxA2 or inflammation, suggesting that the effects of aspirin observed in ...

#70. Aspirin: Dosage & Side Effects | Live Science

Aspirin is a common pain reliever. Learn how aspirin works, what "baby aspirin" is for, what aspirin's side effects are, and whether you ...

#71. Anticoagulant effect of aspirin goes beyond platelet aggregation

Hemonc Today | Aspirin's effect on homeostasis is well-known. Low-dose aspirin (acetylsalicylic acid, 81 mg) inhibits the enzyme Cox-1, ...

#72. Aspirin – low dose | Health Navigator NZ

Find out about the medicine aspirin, when is it used, how much to take and possible side effects.

#73. Aspirin Poisoning Symptoms, Treatment & Long-Term Effects

Aspirin is a trade name for acetylsalicylic acid, a common pain reliever (also called an analgesic). The earliest known uses of the drug can be traced to ...

#74. Aspirin for heart attack: Chew or swallow? - Harvard Health

Immediate first aid works to minimize blood clotting triggered by plaque ruptures. edb7087b-b01a-413d-a0ca-12524213f78a. How should you take aspirin for a heart ...

#75. Effects of nitric oxide-releasing aspirin versus aspirin on ...

Restenosis is due to neointimal hyperplasia, which occurs in the coronary artery after percutaneous transluminal coronary angioplasty (PTCA). During restenosis, ...

#76. Evaluation on antithrombotic effect of aspirin eugenol ester ...

Evaluation on antithrombotic effect of aspirin eugenol ester from the view of platelet aggregation, hemorheology, TXB2/6-keto-PGF1α and ...

#77. Stopping daily aspirin dose can prove deadly - Medical Xpress

Studies have suggested patients experience a "rebound effect" after stopping aspirin treatment, possibly due to increased clotting levels from ...

#78. Aspirin Effect Granulat, 20 St. - DocMorris

Die Tabletten sind mit Einschränkung geeignet bei Zahnschmerzen. Der Wirkstoff von Aspirin®, die Acetylsalicylsäure, verzögert die Blutgerinnung. Das bedeutet, ...

#79. Aspirin, the mighty drug - The Source - Washington University ...

Majerus agreed: “The effect on platelets is long-lasting at such a low dose that it doesn't affect anything else.” COUNTERACTING PROBLEMS. Some ...

#80. Daily aspirin no longer recommended to prevent ... - NBC News

Taking a low-dose aspirin every day to prevent a heart attack or stroke is no longer recommended for most older adults, according to new ...

#81. Aspirin and other common anti-inflammatory drugs could help ...

... such as aspirin to treat the most harmful outcomes of COVID-19. ... or increase the molecules that have an anti-inflammatory effect, ...

#82. Watch out for Your Kidneys When You Use Medicines for Pain

Although aspirin was most common analgesic for decades, today, the most ... People who take too much or take it too often risk side effects or worse.

#83. ASPIRIN Effect Granulat - Beipackzettel | Apotheken Umschau

Wie wirkt der Inhaltsstoff des Arzneimittels? Der Wirkstoff wirkt schmerzstillend, fiebersenkend und entzündungshemmend zugleich. Er blockiert die Bildung ...

#84. ASPIRIN® Effect Granulat 10 St - shop-apotheke.com

Wann wirkt Aspirin Effect? ... Frage von Ruben B. ... Aspirin Effect wirkt gegen Schmerzem, Entzündungen und Fieber und wird bei Alltagsschmerzen, beispielsweise ...

#85. Aspirin Effect: so wirkt die Arznei - NetDoktor

Welche Nebenwirkungen hat Aspirin Effect? ... Häufige Nebenwirkungen sind das Auftreten von Beschwerden im Verdauungstrakt wie Sodbrennen, ...

#86. Aspirin - Family Practice Notebook

Aspirin · Antiinflammatory effect. Inhibits prostaglandin biosynthesis · Analgesic effect. Relieves pain of mild to moderate intensity · Antipyretic (Lowers ...

#87. Effect of low‐dose aspirin on health outcomes - Edinburgh ...

Effect of low‐dose aspirin on health outcomes: An umbrella review of systematic reviews and meta‐analyses. Nicola Veronese, Jacopo Demurtas, ...

#88. Aspirin® Effect – praktisch für unterwegs - medikamente-per ...

Acetylsalicylsäure zählt zu den sogenannten nicht-opioiden Schmerzmitteln sowie zu den nicht-steroidalen Antirheumatika: Das bedeutet, ASS unterdrückt die ...

#89. Comparison Of Protective Effect Of Leukotriene Receptor ...

In our previous 3 month's trial with LTRAs, only 63% of subjects showed good protective effects against aspirin induced bronchospasm, while 37% showed ...

#90. Dispersible aspirin and aspirin - Differences | AXA Health

Gastrointestinal side effects such as nausea, indigestion and vomiting are the most common side effects of aspirin but can be minimised by taking it with ...

#91. Possible Side Effects After Getting a COVID-19 Vaccine | CDC

Helpful Tips to Relieve Side Effects. Talk to a doctor about taking over-the-counter medicine, such as ibuprofen, acetaminophen, aspirin (only for people ...

#92. Aspirin Effect 500 mg, 10 saszetek - cena - Apteka Gemini

Produkt Aspirin Effect 500 mg, 10 saszetek do kupienia w Aptece Internetowej Gemini. Aspirin® Effect firmy Bayer to lek o działaniu przeciwbólowym, ...

#93. Aspirin Effect, 500 mg, granulki w saszetkach, 10 szt. - DOZ.pl

Aspirin Effect to produkt leczniczy do stosowania w bólach różnego pochodzenia jak ból głowy, mięśni, stawów, w gorączce i dolegliwościach związanych z ...

#94. Aspirin® Effect Granulat, schnelle Hilfe bei Kopfschmerzen ...

Aspirin ® Effect Granulat, schnelle Hilfe bei Kopfschmerzen, Einnahme ohne Wasser, perfekt für unterwegs, 20 Stück : Amazon.de: Drogerie & Körperpflege.

#95. Can An Aspirin A Day Keep Atherosclerosis At Bay?

While studies have proven that aspirin can prevent a second heart attack ... these novel effects of low-dose of aspirin are independent from ...