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#1. Prostaglandin EP3 receptor - Wikipedia
Prostaglandin EP3 receptor (53kDa), also known as EP3, is a prostaglandin receptor for prostaglandin E2 (PGE2) encoded by the human gene PTGER3; ...
#2. PTGER3 prostaglandin E receptor 3 [ (human)] - NCBI
2022年9月22日 — EP3 is the primary receptor subtype that mediates PGE(2) induced contractility in human pregnant myometrium at term and represents a possible ...
#3. Prostaglandin E Receptor 3 - an overview | ScienceDirect Topics
The prostaglandin E receptor 3 (EP3) receptors are found on parietal cells of the stomach and, when stimulated, have an inhibitory effect on the proton pump.
#4. PTGER3 - Prostaglandin E2 receptor EP3 subtype | UniProtKB
Variant ID(s) Position(s) Change Disease association CA340769368 rs1262767758 2 K>T No CA906907 rs758581294 5 R>Q No CA906908 rs780890779 5 R>W No
#5. Neuronal prostaglandin E2 receptor subtype EP3 mediates ...
Thus, EP3 receptors may have an important role in body protection by keeping inflammation and pain under control. From this point of view, selective EP3 ...
#6. EP 3 Receptor Polyclonal Antibody - Cayman Chemical
Synthetic peptide from an internal region of human EP3 receptor. Formulation(Request formulation change). 500 µl of peptide affinity-purified antibody.
#7. PTGER3 Gene - GeneCards | PE2R3 Protein
The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for ...
#8. Prostaglandin-E2 receptor EP3 Monoclonal Antibody (5F5)
Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant human EP3 receptor protein and mouse myeloma cells.
#9. EP3 receptor isoforms are differentially expressed in ...
PGE2 is recognized by four distinct G-protein-coupled receptors. Among them, PTGER3 (also known as EP3) is unique in that mRNA splicing generates multiple ...
#10. EP3 receptor antagonist L798,106 reduces proliferation and ...
The EP3 receptor is the least well-understood receptor in breast cancer. We were recently able to demonstrate that EP3 expression in primary ...
#11. Prostanoid EP3 receptor (IPR000265) - InterPro entry
EP3 receptors mediate contraction in a wide range of smooth muscles, including gastrointestinal and uterine. They also inhibit neurotransmitter release in ...
#12. Prostaglandin E2 sensitizes the cough reflex centrally via EP3 ...
Whilst all the EP receptors have been reported to have airway effects, good evidence suggests that the EP3 receptor is the main receptor ...
#13. EP3 Receptor Deficiency Improves Vascular Remodeling and ...
Elevated EP3 receptor expression has been reported in the small arteries of hypertensive animals [13], and inhibition of EP3 receptors has been shown to reverse ...
#14. Polyclonal Antibody to Prostaglandin E Receptor 3 (EP3)_ ...
Alternative Names : PTGER3; EP3-I; EP3-II; EP3-III; EP3-IV; EP3e; PGE2 receptor EP3 subtype; Prostanoid EP3 receptor. Item Name : Prostaglandin E Receptor 3.
#15. EP3 Receptor Antibodies
Serine369/Serine370 (S369/S370) is major phosphorylation site of the EP3 Prostanoid Receptor (EP3). The pS369/pS370-EP3 antibody detects phosphorylation in ...
#16. EP 3 receptor - IUPHAR/BPS Guide to PHARMACOLOGY
The IUPHAR/BPS Guide to Pharmacology. EP 3 receptor - Prostanoid receptors. Detailed annotation on the structure, function, physiology, pharmacology and ...
#17. Rat prostaglandin EP3 receptor is highly promiscuous and is ...
Here, we define EP3 as the sole prostanoid receptor family member expressed in a rat β-cell-derived line that regulates glucose-stimulated ...
#18. Essential role of prostaglandin E2 and the EP3 receptor in ...
The EP2 and EP4 receptors are coupled to Gs and increase intracellular cAMP concentrations via the activation of adenylyl cyclase. The EP3 ...
#19. The Prostaglandin E2-EP3 Receptor Axis Regulates ... - PLOS
(2016) The Prostaglandin E2-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation.
#20. Sulprostone, EP1/ EP3 receptor agonist (ab120907) - Abcam
Selective EP1/ EP3 receptor agonist. PGE2 analog. CAS Number: 60325-46-4; Purity: > 98%; Supplied in methyl acetate (10 mg/ ...
#21. Human Islet Expression Levels of Prostaglandin E 2 Synthetic ...
(7,9−12) Our and others' previous studies suggest that signaling through prostaglandin EP3 receptor (EP3), a G protein-coupled receptor for the ...
#22. Prostaglandin-E2 receptor EP3 antibody - Biorbyt
Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant human EP3 receptor protein and mouse myeloma cells. Target, Prostaglandin- ...
#23. The Roles Played by FP/EP3 Receptors During Pressure ...
IOP reduction at 6 hours was significantly higher after simultaneous administration of selective FP and EP3 receptor agonists, but IOP did not fall on ...
#24. EP3 (E-Prostanoid 3) Receptor Mediates Impaired ...
EP3 (E-Prostanoid 3) Receptor Mediates Impaired Vasodilation in a Mouse Model of Salt-Sensitive Hypertension. Jing Wu; ,; Shi Fang; ,; Ko-Ting ...
#25. Functional Analysis of the Prostaglandin EP3 Receptor
The EP3 receptor is the unique among the EP receptor family in that it is represented by multiple alternatively spliced variants generated by alternative ...
#26. PTGER3 - prostaglandin E receptor 3 (subtype EP3)
The human EP3 receptor subtype protein was strongly expressed in glomeruli, Tamm-Horsfall negative late distal convoluted tubules, connecting segments, cortical ...
#27. Prostaglandin E Receptor EP3/PTGER3 Blocking Peptide
A Blocking Peptide for Anti-Prostaglandin E Receptor EP3/PTGER3 Antibody.
#28. Downregulation of prostaglandin E receptor subtype EP3 ... - Gut
Methods: mRNA expression of PGE2 receptor subtypes EP1, EP2, EP3, and EP4 in normal colon mucosa and colon cancers in azoxymethane (AOM) treated mice and rats, ...
#29. The PGE 2 EP3 Receptor Regulates Diet-Induced Adiposity in ...
Abstract. Mice carrying a targeted disruption of the prostaglandin E2 (PGE2) E-prostanoid receptor 3 (EP3) gene, Ptger3, were fed a high-fat diet (HFD), ...
#30. C58. ACUTE LUNG INJURY: ATYPICAL TRIGGERS
C58. ACUTE LUNG INJURY: ATYPICAL TRIGGERS · Inhibition of the EP3 Receptor for Prostaglandin E2 Attenuates Airway Injury Following Acute Exposure to Chlorine.
#31. The prostaglandin E2 receptor EP3 controls CC-chemokine ...
Interestingly, of the four PGE2 receptors, only deletion of the EP3 receptor decreased late stage trauma-induced mechanical allodynia. EP3 ...
#32. 6M9T: Crystal structure of EP3 receptor bound to misoprostol-FA
Crystal structure of EP3 receptor bound to misoprostol-FA · Crystal structure of misoprostol bound to the labor inducer prostaglandin E2receptor.
#33. Advances in the Study of EP3 Receptor Signaling | Request PDF
PGE receptors are divided into four subtypes, EP1, EP2, EP3, and EP4, which have been identified and cloned. These EP receptors are members of ...
#34. Activation of the murine EP3 receptor for PGE 2 inhibits cAMP ...
Consistent with these findings, loss of the EP3 receptor in a model of venous inflammation protects against formation of intravascular clots. Our results ...
#35. Prostaglandin EP3 receptor-expressing preoptic neurons ...
The circuit mechanism of the thermoregulatory center in the preoptic area (POA) is unknown. Using rats, here we show prostaglandin EP3 receptor- ...
#36. Prostaglandin E2 receptor EP3 subtype | DrugBank Online
Name: Prostaglandin E2 receptor EP3 subtype; Synonyms. PGE receptor EP3 subtype; PGE2-R; Prostanoid EP3 receptor. Gene Name: PTGER3; Organism: Humans ...
#37. The Prostaglandin EP3 Receptor Is an Independent Negative ...
In this study we could show that the membrane-bound prostaglandin receptor EP3 is an independent prognosticator for cervical cancer patient survival.
#38. Anti-EP3 Receptor | Cayman Chemical | Biomol.com
The EP3 receptor is expressed in a variety of tissues with highest levels in kidney, pancreas, and uterus. Synonyms: PGE2 Receptor 3, Prostaglandin E2 Receptor ...
#39. Antagonists of the EP3 receptor for prostaglandin E2 are novel ...
Myocardial infarction and stroke are caused by blood clots forming over a ruptured or denuded atherosclerotic plaque (atherothrombosis).
#40. Cyclooxygenase-2 dependent prostaglandin E2 signaling ...
Cyclooxygenase-2 dependent prostaglandin E2 signaling through the EP3 receptor is required for cell-mediated immunity to Listeria monocytogenes.
#41. L-798106 (CM9) | EP3 Receptor Antagonist - MedChemExpress
L-798106 is potent and highly selective prostanoid EP3 receptor antagonist (Ki=0.3 nM), it also has micromolar activities at the EP4, EP1 and EP2 receptors ...
#42. Prostaglandin E2 receptor 3 (EP3) signaling promotes ...
Prostaglandin E2 receptor 3 (EP3) signaling promotes migration of cervical cancer via urokinase-type plasminogen activator receptor (uPAR).
#43. Stimulation of the EP3 receptor causes lung edema by ...
Stimulation of the EP3 receptor causes lung edema by activation of TRPC6 in pulmonary endothelial cells. Tian Jiang, Rudi Samapati, Sergej Klassen, ...
#44. Host Prostaglandin E2-EP3 Signaling Regulates Tumor ...
Application of an EP3 receptor antagonist inhibited tumor growth and angiogenesis in WT, but not in EP3 −/−. These results demonstrate significance of host ...
#45. The deleterious role of the prostaglandin E 2 EP 3 receptor in ...
This study is the first to show that systemic treatment with an EP3 receptor antagonist (L798,106) attenuates the angiotensin II-induced ...
#46. EP1- and EP3-Receptors Mediate Prostaglandin E2–Induced ...
ting also showed the presence of EP1- and EP3-receptor pro- teins in cultured primary cerebral vascular smooth muscle cells. In conclusion, PGE2 exclusively ...
#47. EP3 Human Prostanoid GPCR Cell Based Antagonist cAMP ...
Prostanoid EP3 receptors are present in brain, kidney, eye, uterus and the gastrointestinal tract. The EP3 receptor agonism plays a role in digestion, ...
#48. PTGER3 / EP3 - LSBio
prostaglandin E receptor 3 (subtype EP3). Receptor for prostaglandin E2 (PGE2); the EP3 receptor may be involved in inhibition of gastric ...
#49. Prostanoid EP3 receptor Gene Set
Genes. 1 proteins predicted to have the Prostanoid EP3 receptor protein domain from the InterPro Predicted Protein Domain Annotations dataset.
#50. Prostaglandin E2 Receptor, EP3, Is Induced in Diabetic Islets ...
The EP3 receptor is stimulated by prostaglandin E2 (PGE2) and couples to G-proteins of the Gi subfamily to decrease intracellular cAMP, blunting ...
#51. Showing Protein Prostaglandin E2 receptor EP3 subtype ...
Specific Function, Receptor for prostaglandin E2 (PGE2); the EP3 receptor may be involved in ... g-protein coupled receptor protein signaling pathway ...
#52. Prostaglandin receptor EP3 regulates cell proliferation and ...
Background: Prostaglandin E2 (PGE2) receptor 3 (EP3) regulates tumor cell proliferation, migration, and invasion in numerous cancers. The role ...
#53. The Prostaglandin EP3 Receptor Is an Independent Negative ...
The Prostaglandin EP3 Receptor Is an Independent Negative Prognostic Factor for Cervical Cancer Patients [2017]. Helene Heidegger; Sebastian Dietlmeier; ...
#54. Exploring a New Target for Type 2 Diabetes Therapeutics
Furthermore, increased islet PGE2 production and EP3 expression have a negative impact on signaling through the GLP-1 receptor, which in beta-cells is a strong, ...
#55. Prostaglandin E1 attenuates AngII-induced cardiac ...
The activation of EP3 receptor by PGE1 leads to up-regulation of Ntn1, which inhibits the MAPK signaling pathway. •. PGE1-EP3 as well as ...
#56. Prostaglandin E2 Impairs P2Y2/P2Y4 Receptor Signaling in ...
Activation of EP3 receptors by PGE2 not only impairs the calcium responses but also, the extracellular regulated kinases (ERK) and Akt ...
#57. "The Prostaglandin E2-EP3 Receptor Axis Regulates ...
PGE2-EP3 receptor signaling leads to activation of the NLRC4 inflammasome and ... Importantly, the receptor-interacting serine/threonine-protein kinase 2 ...
#58. EP 3 signaling suppresses skin inflammation in murine ...
Prostaglandin (PG) E2 exerts a variety of actions through 4 G protein–coupled receptors designated as EP1, EP2, EP3, and EP4.
#59. Expression of PGE2 EP3 receptor subtypes in ... - DiVA portal
Inflammatory-induced fever is dependent on prostaglandin E2 (PGE2) binding to its EP3 receptor in the thermoregulatory region of the ...
#60. Antagonists of prostaglandin EP3 receptor - WIPO Patentscope
Provided herein are antagonists of prostaglandin EP3 receptor, processes to make said antagonists, and methods comprising administering said antagonists to ...
#61. PROSTAGLANDIN E RECEPTOR 3, EP3 SUBTYPE ... - OMIM
PROSTAGLANDIN E RECEPTOR 3, EP3 SUBTYPE; PTGER3. HGNC Approved Gene Symbol: PTGER3. Cytogenetic location: 1p31.1 Genomic coordinates (GRCh38): ...
#62. The EP3 Agonist Sulprostone Enhances Platelet Adhesion But ...
Platelets express the EP2, EP3 and EP4 receptors. Prostaglandin (PG) E2 has a biphasic effect on platelets. Low concentrations of PGE2 ...
#63. Inhibition of the prostaglandin E2 EP3 receptor does not affect ...
... when signaling via its EP3 receptor subtype and that EP3 expression increases in ... that inhibition of EP3 would also antagonize beta adrenergic signaling.
#64. Lack of Expression of the EP2 but not EP3 Receptor for ...
The purpose of this study was to investigate the role of the EP2 receptor in mouse skin carcinogenesis. Unlike EP3 knockout mice, the EP2 knockout mice ...
#65. EP3 (prostaglandin E2 receptor 3) expression is a prognostic ...
EP3 receptor expression was not associated with clinicopathological parameters (e. g. tumor size, hormone receptors, lymph node status). Kaplan- ...
#66. Rostral Ventrolateral Medulla EP3 Receptor Mediates the ...
To achieve these goals, we showed the expression of EP2, EP3, and EP4 receptors in the RVLM and investigated their cardiovascular roles in ...
#67. P8.6 Different populations of prostaglandin EP3 receptor ...
P8.6 Different populations of prostaglandin EP3 receptor-expressing rat preoptic neurons project to two fever-mediating sympathoexcitatory brain regions.
#68. Host prostaglandin EP3 receptor signaling relevant to tumor ...
Biomedicine and pharmacotherapy - Vol. 64 - N° 2 - p. 101-106 - Host prostaglandin EP3 receptor signaling relevant to tumor-associated lymphangiogenesis ...
#69. Inflammation leads through PGE/EP3 signaling to HDAC5 ...
Each of the four types is expressed in cardiac myocytes, but EP3 and EP4 receptors are the most abundant isoforms (Di Benedetto et al, 2008). The EP3 receptor ...
#70. The EP3 Receptor/Gz Signaling Axis as a Therapeutic Target ...
This review will focus on one molecular signaling pathway: that mediated by the G protein-coupled receptor, Prostaglandin E2 Receptor 3 ...
#71. Immunolocalization of the Four Prostaglandin E2 Receptor ...
Abstract. Four prostaglandin E2 receptor subtypes designated EP1, EP2, EP3, and EP4 have been shown to mediate a variety of effects of ...
#72. EP3-Rezeptor - DocCheck Flexikon
Der EP3-Rezeptor ist ein Rezeptor für Prostaglandin E2. Er zählt zu den Gi-gekoppelten Rezeptoren.
#73. PROSTAGLANDIN E2 RECEPTOR EP3 SUBTYPE
物质名称, PROSTAGLANDIN E2 RECEPTOR EP3 SUBTYPE. 异名/同义词, PGE2-R PROSTAGLANDIN E2 RECEPTOR EP3 SUBTYPE PROSTANOID EP3 RECEPTOR. CAS登记号.
#74. An Update of Microsomal Prostaglandin E Synthase-1 and ...
The modulation of the four EP receptors in cardiovascular system is diversely ... EP3 receptor mainly couples to -proteins to decrease cAMP production, ...
#75. PTGER3 induces ovary tumorigenesis and confers resistance ...
Inflammatory mediator prostaglandin E2–prostaglandin E2 receptor EP3 (PTGER3) signaling is critical for tumor-associated angiogenesis, ...
#76. Regulation of renal function by prostaglandin E receptors
EP3 receptor activation also may contribute to PGE2-mediated inhibition of NaCl absorption in the mTAL. The EP1 receptor is coupled to increased cell [Ca 2+ ]. EP ...
#77. Receptors, Prostaglandin E, EP3 Subtype
Learn about Receptors, Prostaglandin E, EP3 Subtype at online-medical-dictionary.org. ... Prostaglandin E2 Receptor, EP3 Subtype. Prostanoid Receptor EP3.
#78. Essential Fatty Acids and Eicosanoids: Invited Papers from ...
The current classification of prostanoid receptors . ... No attempt has been made to present all of the splice variants of the EP3 - receptor ( see text ) ...
#79. Prostaglandin EP3 receptor (53kDa), also known as EP3, is a ...
Prostaglandin EP3 receptor (53kDa), also known as EP3, is a prostaglandin receptor for prostaglandin E2 (PGE2) encoded by the human gene PTGER3; ...
#80. Middleton's Allergy E-Book: Principles and Practice
Mouse Allergic Studies Inflammation of Prostaglandin E2 in In the OVA-sensitization and challenge model, mice that are deficient in the EP3 receptor had ...
#81. Brenner and Rector's The Kidney E-Book - 第 372 頁 - Google 圖書結果
febrile response, suggesting that EP3 receptor antagonists could be effective antipyretic agents.266 Other studies have suggested that the EP3 receptor ...
#82. Eicosanoids and Other Bioactive Lipids in Cancer, ...
Another is that there are several isoforms present for EP3 . In order to clarify this point , we carried out cDNA cloning of EP3 receptor from cDNA library ...
#83. Molecular Neuroscience - 第 77 頁 - Google 圖書結果
The activation of the receptor subtype EP3 for prostaglandin E2 (PGE2) can produce increases or decreases in cAMP levels. Four isoforms of the EP3 receptor ...
#84. Eicosanoids: Advances in Research and Application: 2011 Edition
... in the report 'Recruited bone marrow cells expressing the EP3 prostaglandin E receptor subtype enhance angiogenesis during chronic inflammation.
#85. Autacoids: Advances in Research and Application: 2011 Edition
Intraplantar injection of LTC4, a CysLT2 receptor agonist, itself did not ... cough via the EP3 receptor: implications for future disease therapy,' new data ...
#86. Psychoneuroimmunology - 第 327 頁 - Google 圖書結果
... 540 600 660 FIGURE 5 Effects of intraperitoneal injection of LPS at 100 μg/kg on core temperature (T) in WT, EP1 receptor KO, and EP3 receptor KO mice.
#87. Handbook of Neuroendocrinology - 第 406 頁 - Google 圖書結果
PGE2 binds to four different Gprotein coupled receptors, referred to as EP1e4. ... The control of fever is mediated primarily by the EP3 receptor, ...
#88. The Epithelial Cell-Derived Atopic Dermatitis Cytokine TSLP ...
We define a subset of sensory neurons that require both functional TSLP receptors and the ion channel, TRPA1, to promote TSLP-evoked itch ...
#89. Hypertension Clinical Trials Pipeline Analysis - Yahoo Finance
Prostaglandin E EP3 receptor agonists; Prostaglandin F2 alpha agonists. Ophthalmic. NCX 470. Nicox. Phase III. Nitric oxide donors.
#90. Hypertension Clinical Trials Pipeline Analysis - EIN News
... Idorsia's dual endothelin receptor antagonist, for the treatment of ... Prostaglandin E EP3 receptor agonists; Prostaglandin F2 alpha ...
#91. Hypertension Clinical Trials Pipeline Analysis: 90+
... Idorsia's dual endothelin receptor antagonist, for the treatment of ... Prostaglandin E EP3 receptor agonists; Prostaglandin F2 alpha ...
#92. 乳癌教育防治講座【Neratinib® (Nerlynx)賀儷安於HER-2過度 ...
Description · 賴鴻文醫師乳癌教育防治講座【癌因性疲憊EP.3 - 癌因性疲憊造成的影響】#乳癌#疲憊#懷特血寶#化療 · Sugar: The Bitter Truth · How to Make ...
#93. Emerging Therapies for Pediatric Atopic Dermatitis Management
Alexa mentioned the aryl hydrocarbon receptor agonist as a topical target, which is exciting because it's nonsteroidal and seems to have ...
#94. 7 foods that can help you poop and relieve constipation
Castor oil induces laxation and uterus contraction via ricinoleic acid activating prostaglandin EP3 receptors. Proceedings of the National Academy of ...
#95. Role of the Broader Healthcare Team in Managing AEs ...
... of life vs physicians choice of treatment in patients with advanced, hormone receptor–positive/HER2-low metastatic breast cancer.
#96. How long does angioedema from lisinopril last. Feb 08, 2016
... is an ACE-Inhibitor while Losartan in an angiotensin II receptor blocker. ... 1998 ford f700 engine specs; albertsons hourly pay; ep3 battery light on.
#97. Subtipo de receptor EP4 de prostaglandina E2 Tamaño del ...
El informe de investigación de mercado de Subtipo de receptor EP4 de ... los otros son EP1, EP2 y EP3, todos los cuales se unen y median las ...
#98. Tamanho emergente do mercado PROSTAGLANDIN E2 ...
O tamanho do mercado global de subtipos de subtipo de receptor E2 da ... EP2 e EP3, que se ligam e mediam as respostas celulares ao PGE2 e ...
ep3 receptor 在 乳癌教育防治講座【Neratinib® (Nerlynx)賀儷安於HER-2過度 ... 的推薦與評價
Description · 賴鴻文醫師乳癌教育防治講座【癌因性疲憊EP.3 - 癌因性疲憊造成的影響】#乳癌#疲憊#懷特血寶#化療 · Sugar: The Bitter Truth · How to Make ... ... <看更多>