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#1. 胰島素增敏劑—— thiazolidinediones - 內科醫學會
Glitazones 的作用機制主要是作用在細胞核內稱為peroxisome, proliferator-activated receptor ( PPAR ) 的接受器4。 PPAR 的發現是1990 年代以後的事情,歷史很短。目前 ...
#2. Glitazones: clinical effects and molecular mechanisms - PubMed
With the thiazolidinediones rosiglitazone and pioglitazone a novel treatment modality for type 2 diabetes has become available in many countries.
#3. Thiazolidinedione - Wikipedia
əˌzoʊlɪdiːnˈdaɪ.oʊn/, abbreviated as TZD, also known as glitazones after the prototypical drug ciglitazone, ...
#4. List of Thiazolidinediones (glitazones) - Drugs.com
Thiazolidinediones (also called glitazones) are a class of medicines that may be used for the treatment of type 2 diabetes. They are a type of oral ...
#5. Thiazolidinediones (Glitazones) - Suitability, Benefits & Side ...
Thiazolidinediones, also known as glitazones, are a group of oral anti-diabetic drugs designed to treat patients with type 2 diabetes.
#6. Glitazones and Heart Failure | Circulation - AHA Journals
Thiazolidinediones (TZD; glitazones) are peroxisome proliferator-activated receptor (PPAR) agonists that specifically augment insulin sensitivity and counter ...
#7. The Rise and Fall of the Glitazones - FullText
Enter the Glitazones ... Clofibrate, the first of the lipid-lowering fibrates, was introduced 25 years before its target was known. Others followed, and ...
#8. Fluid Retention, Cardiac Failure and Macular Oedema
The glitazones (also known as thiazolidinediones or TZDs) are used in the treatment of Type 2 diabetes mellitus. They are the first class of medicines to ...
#9. Glitazones and alpha-glucosidase inhibitors as the second ...
Glitazones and alpha-glucosidase inhibitors as the second-line oral anti-diabetic agents added to metformin reduce cardiovascular risk in Type 2 ...
#10. Glitazone Derivative - an overview | ScienceDirect Topics
Thiazolidinediones (TZDs), also known as glitazones, are insulin sensitizers. They act on target tissues to decrease insulin resistance. They bind to PRAY, a ...
#11. Glitazones - Prices and Information - GoodRx
Compare prices and find information about Glitazones prescription drugs. Glitazones are used to treat diabetes type 2 and PCOS. They work by making...
#12. Glitazones and NIDDM - The Lancet
comment that thiazolidinedione derivatives (“glitazones”, including troglitazone), which alter fatty acid metabolism via peroxisome ...
#13. Two Rationally Identified Novel Glitazones Reversed the ...
The present study has planned to evaluate the neuroprotective activity of two novel glitazones in a neuroinflammatory rat model.
#14. What are glitazones? - SingleCare
Technically known as thiazolidinediones (TZDs), the glitazones are a family of drugs used sparingly for the treatment of Type 2 diabetes ...
#15. The use of glitazones (thiazolidinediones) in heart failure
The use of glitazones (thiazolidinediones) increases the risk of worsening of heart failure and admissions for congestive heart failure.
#16. Gliptins and Glitazones Aren't Associated with Adverse ...
The oral glucose-lowering drug classes known as dipeptidyl peptidase-4 inhibitors (gliptins) and thiazolidinediones (glitazones) have been ...
#17. Have glitazones lost their sparkle? - Australian Prescriber
Health professionals and consumers have become more aware of this with the removal of widely used drugs such as rofecoxib from the market. Now ...
#18. Thiazolidinediones (TZDs or Glitazones) for Type 2 Diabetes
Thiazolidinediones—often called TZDs or glitazones—can lower your insulin resistance. This medication helps your body use insulin better, ...
#19. (PDF) The Story of Glitazones - ResearchGate
PDF | On Jan 1, 2011, Madhav Mutalik published The Story of Glitazones | Find, read and cite all the research you need on ResearchGate.
#20. Thiazolidinediones (glitazones) | Diabetes UK
Thiazolidinediones (glitazones) ... The only tablet in this group is pioglitazone. This works by reducing insulin resistance and improving insulin sensitivity, ...
#21. Which medications in the drug class Thiazolinediones ...
Thiazolinediones (glitazones)The first of this class, troglitazone, was removed from the US market due to fatal hepatic necrosis.
#22. Glitazones, PPAR-γ and Neuroprotection - Bentham Science ...
This review gives an insight that ligand-dependent activation of PPAR-γ by glitazones could initiate the structural conformational changes ...
#23. [A05-05A] Glitazones in the treatment of diabetes mellitus type 2
Glitazones have not yet been sufficiently investigated. No long-term studies on rosiglitazone available / Pioglitazone could reduce risk of ...
#24. Glitazones (Actos and Avandia) - Straight Healthcare
Review of glitazones (Actos and Avandia) including efficacy, side effects, precautions, drug interactions, and more.
#25. Glitazones Activate PGC-1α Signaling via PPAR-γ
(115) Glitazones treatment, through its ability to upregulate PGC-1α expression, has been shown to increase the brain mitochondrial biogenesis ...
#26. Glitazones, Glycemia, and Global Health Status | Diabetes Care
Despite improved glycemia and other potential cardiovascular benefits of thiazolidinediones (2), at some point, weight gain, which is common, significant, and ...
#27. Glitazones: Evidence to inform daily practice - Wounds ...
The glitazones are oral anti-diabetes agents that have been available for 7 years in the UK. In September 2002, NICE published guidelines on managing blood ...
#28. Influence of Glitazones on the Vasodilatory Effect of High ...
The primary objective of the study is to analyze whether treatment with glitazones (pioglitazone and rosiglitazone)may improve the endothelium-dependent ...
#29. Getting to know the glitazones | Medicine Today
The 'glitazones' are a new class of compounds for the treatment of type 2 diabetes. They exert their glucose-lowering effect by improving the sensitivity of ...
#30. The “Glitazones”: Rosiglitazone and Pioglitazone - Journal of ...
Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes mellitus: a ...
#31. Thiazolidinediones (Glitazones) - Western Health
Glitazones are used with a diet and exercise program in patients with Type 2 diabetes. Glitazone may be used alone or with other medications to control blood ...
#32. Glitazones (thiazolidinediones) - The British Journal of ...
Glitazones improve glycaemic control in type 2 diabetes mellitus (T2DM) by increasing whole-body insulin sensitivity.
#33. Glitazones are associated with reduced risk of Parkinson's ...
Patients who take the antidiabetes drugs rosiglitazone or pioglitazone have a lower risk of developing Parkinson's disease than patients ...
#34. The sweetness of glitazones: randomized trials needed - Nature
Two observational studies report opposite effects of glitazones on clinical outcomes in patients with ESRD. Given the limited reliability of such studies in ...
#35. Glitazones Exert Multiple Effects on β-Cell Stimulus-Secretion ...
Earlier studies suggest that glitazones exert beneficial effects in patients with type 2 diabetes by directly affecting insulin secretion of ...
#36. ASCO: Glitazones Take New Hit for Bladder Ca Risk
The increased risk of bladder cancer associated with glitazones -- which reached a relative increase of 72% in patients who started on the agents more than ...
#37. Glitazones in Clinical Practice: The Effect on Insulin Resistance
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#38. Nice timing for glitazones - Clifford J Bailey, Caroline Day ...
The National Institute for Clinical Excellence (NICE) recently revised its guidance on the use of thiazolidinediones (TZDs). Days later, the European Agency ...
#39. Glinides and glitazones in the treatment of type 2 diabetes
The aim of the short report is to assess the efficacy and safety of glinides and glitazones in treating patients with type 2 diabetes ...
#40. New Oral Therapies for Type 2 Diabetes Mellitus - Annual ...
The glitazones have been shown to have beneficial effects not only on peripheral insulin sensitivity, hepatic glucose metabolism, and lipid metabolism but ...
#41. Glitazones - Thiazolidinediones - GlobalRPH
Glitazones , Thiazolidinediones, rosiglitazone, Avandia, pioglitazone ,Actos, Avandamet.
#42. Effect of glitazones on the progression of coronary artery ...
Effect of glitazones on the progression of coronary artery disease in type 2 diabetes patients Jamison Wyatt1, Shailesh Nandish1, ...
#43. Glitazones have not yet been sufficiently inv | EurekAlert!
Glitazones improve insulin sensitivity in the adipose tissue, skeletal muscle, and liver. As a result, glucose uptake by the adipose tissue ...
#44. Pioglitazone, Rosiglitazone, and Troglitazone
#45. Analysts compare and contrast new glitazones from SB and ...
Analysts compare and contrast new glitazones from SB and Takeda. analysts, compare, contrast, new, glitazones, sb, takeda.
#46. CROI: Disappointment for glitazones, metformin and ...
Is pioglitazone better than rosiglitazone at restoring lost fat? Although the exact causes of lipoatrophy (fat loss) in HIV-positive individuals ...
#47. Glitazones - DynaMed
We use cookies to give you a better experience on our sites. To learn more about how we use cookies, please read our privacy policy. accept cookies ...
#48. molecular design, synthesis, glucose uptake activity and 3D ...
Glitazones such as ragaglitazar, MK-0767, aleglitazar and navegli- tazar, just to name a few, have exhibited clinical utility to glycaemic control and insulin ...
#49. A licence change for the glitazones - DiabetesontheNet
Sulphonylureas, metformin and the glitazones are all effective drugs at lowering blood glucose levels. In clinical trials, all these drugs ...
#50. Reimbursement of glitazones in treatment of ... - SpringerLink
The study concludes that the voluntary system has not supported the inclusion of efficiency considerations in reimbursement decision making on glitazones. The ...
#51. GLITAZONES & FRACTURE RISK - SlideShare
GLITAZONES & FRACTURE RISK · 1. GLITAZONES & THEIR FRACTURE RISK Prof. · 2. Introduction <ul><li>Glitazones enhance insulin sensitivity in the adipose tissue, ...
#52. Peritoneal Infection and Inflammation - Hindawi
Activation of Peroxisome Proliferator-Activated Receptor-Gamma by Glitazones Reduces the Expression and Release of Monocyte Chemoattractant Protein-1 in Human ...
#53. Glitazones Differentially Regulate Primary Astrocyte and ...
We determined the effects of two glitazones, ciglitazone and the therapeutic rosiglitazone, on the survival of serum-deprived primary rat astrocytes and ...
#54. glitazones - General Practice Notebook
glitazones · clinical trials with both pioglitazone and rosiglitazone have shown no serious hepatotoxity - however monitoring of liver function tests is advised ...
#55. 1. wo2010150014 - 5r- 5 -deuterated glitazones for respiratory ...
WO2010150014 - 5R- 5 -DEUTERATED GLITAZONES FOR RESPIRATORY DISEASE TREATMENT. Publication Number WO/2010/150014.
#56. Development of Novel Glitazones as Antidiabetic Agents
Further, within the cytotoxicity window, glitazones were screened for glucose uptake activity against L6 cells to assess their possible ...
#57. Glitazones & COVID-19: The Role Beyond Sugar Management
Glitazones are a class of drugs employed in sugar management in diabetic patients. It is observed that people with diabetes fall under the ...
#58. Secondary Catalogue - A Brief Guide to Glitazones - ClickView
Glitazones help increase the insulin sensitivity in patients with Type 2 Diabetes. This short clip explains when and how glitazones are used to...
#59. Pharmacological Differences of Glitazones - JACC
Pharmacological Differences of Glitazones: Does Peroxisome Proliferator-Activated Receptor-α Activation Make the Difference? ⁎ ⁎.
#60. Glinides and Glitazones for Type 2 Diabetes Mellitus - SGED ...
glinides (repaglinide and nateglinide), and glitazones (pioglitazone) for treatment of type 2 diabetes mellitus (T2DM) to inform whether ...
#61. glitazones - Wiktionary
Wiktionary. Search. glitazones. Language · Watch · Edit. EnglishEdit. NounEdit. glitazones. plural of glitazone. AnagramsEdit · nostalgize.
#62. Importance of sulfoxidation in rapid racemisation of glitazones
We have carried out semi-empirical. AM1 calculations on glitazones and some non- thiazolidinedione derivatives to understand the importance of sulfoxides in the ...
#63. Impact of glitazones on metabolic and haemodynamic ...
Impact of glitazones on metabolic and haemodynamic parameters in patients with type 2 diabetes mellitus. Abstract; PDF. Chogtu B, Singh NP, Chawla S, ...
#64. Glinides and glitazones in the treatment of type 2 diabetes
Technology Description: Glinides and glitazones are oral glycaemic control medications for patients with T2DM. Although evidence suggests that glinides and ...
#65. traitement diabete type 2, Glitazone, Avandia, Actos
Les glitazones sont maintenant interdites en raison de leurs effets secondaires : il s'agissait de l' Actos (Pioglitazone Competact) et de la Rosiglitazone ...
#66. Use of glitazones in cardiac patients: a case for B-type ...
Glitazones (thiazolidinediones) belong to the pharmacologic group of insulin sensitizers. Currently, pioglitazone and rosiglitazone are available for clinical ...
#67. Thiazolidinediones (glitazones) - Medicine Matters diabetes
Thiazolidinediones (glitazones). In the news. Brain scan. 04-08-2021 | Stroke | News. Genetic analysis backs causal link between blood glucose and stroke.
#68. 6.1.2.4 Glitazones (thiazolidinediones) | NI Formulary
6.1.2.4 Glitazones (thiazolidinediones). Choice, Drug, Dosage. Formulary choice, Pioglitazone tablets 15mg, 30mg, 45mg, Dose: ...
#69. Reimbursement of Glitazones in Treatment of Type 2 ... - jstor
Reimbursement of glitazones in treatment of type 2 diabetes patients in Denmark in the context of a voluntary system for submit-.
#70. Thiazolidinedione Use (glitazones), Fluid Retention ... - NATAP
Thiazolidinedione Use (glitazones), Fluid Retention, and Congestive Heart Failure. A Consensus Statement From the American Heart Association and American ...
#71. Fibrates, glitazones, and peroxisome proliferator-activated ...
Fibrates and glitazones: classical pharmacology and clinical use. Fibrates, glitazones and PPARs: from classic to molecular pharmacology.
#72. Glitazones: Good for Glycemia. Good for the Liver? - Mary Ann ...
"Glitazones: Good for Glycemia. Good for the Liver?." , 5(1), pp. 43–44. Figures; References; Related; Details. Cited By.
#73. Metformin, Sulfonylureas, Glitazones - Polypharmacy: Manage ...
Metformin, Sulfonylureas, Glitazones. ... Metformin, Sulfonylureas, Glitazones. Print this page. Open all sections. Chapter 6: Endocrine system.
#74. Novartis starts major study of Galvus versus glitazones
Swiss drug major Novartis has started a large-scale clinical trial programme that will compare its investigational oral type 2 diabetes ...
#75. The use of glitazones in diabetes | GPonline
Viewpoint: There has been much discussion over the use of glitazones in diabetes. Dr Mark O'Mahony and Dr Azhar Farooqi offer both sides of ...
#76. Glitazone Compounds - Dalton Research Molecules
Dalton's Glitazones are manufactured to the highest quality standards. Learn more about our Glitazone Compounds.
#77. Peroxisome Proliferator Activated Receptors: From Basic ...
Thus the antihyperglycemic effect of glitazones as judged by changes of fasting blood glucose and HbA1c are modest and less than observed when SUs and ...
#78. “Glitazones as First Line Therapy in Type 2 Diabetes” - IUPUI ...
GLITAZONES. Modes of Action. • It activates the nuclear peroxisome proliferator activated receptor - (PPAR- ). • It also has partial agonist activity ...
#79. Pioglitazone: medicine to treat type 2 diabetes - NHS
Pioglitazone belongs to a group of diabetes medicines called thiazolidinediones (or glitazones). It helps control blood sugar levels by improving how your ...
#80. Glitazones in the treatment of type 2 diabetes | Guidance | NICE
Glitazones in the treatment of type 2 diabetes. Technology appraisal guidance [TA63] Published: 27 August 2003 ...
#81. Glitazones and the management of insulin resistance
Thiazolidinediones (glitazones) are the only compounds currently available ... The glitazones are highly selective and potent synthetic agonists for the ...
#82. Glitazones are associated with reduced risk of COPD ...
Abstract. Introduction: Moderators of systemic inflammation may reduce risk of exacerbations among patients with COPD. Glitazones, used in the treatment of ...
#83. resultats des etudes PROactive, ADOPT, DREAM et RECORD.
Reference : Glitazones et insuffisance cardiaque: resultats des etudes PROactive, ADOPT, DREAM et... Document type : Scientific journals : Article.
#84. Diabetic Cardiology - 第 114 頁 - Google 圖書結果
An increase in subcutaneous fat and a decrease in visceral fat have been demonstrated in patients with diabetes treated with glitazones (Miyazaki etal., ...
#85. Glitazones regulate glutamine metabolism by inducing a ...
We studied the effect of the antihyperglycemic glitazones, ciglitazone, troglitazone, and rosiglitazone, on glutamine metabolism in renal tubule-derived ...
#86. Pleiotropic effects of glitazones: a double edge sword?
effects induced by glitazones is far from being complete, but may give an idea of the multiplicity of genes regulated following PPARγ.
#87. Canadian study in elderly finds glitazones increase heart risk
Canadian study in elderly finds glitazones increase heart risk. December 13, 2007. Glitazone study shows CV risk may be higher for elderly.
#88. Glitazones in bladder cancer - Clinical Advisor
The thiazolidinedione pioglitazone, which targets insulin resistance in type 2 diabetes, demonstrated no connection with bladder cancer in ...
#89. Définition | Glitazone - Thiazolidinedione | Futura Santé
Les glitazones sont des molécules hypoglycémiantes. Elles agissent en se liant à des récepteurs présents dans les cellules adipeuses des muscles et du foie. L' ...
#90. Rein et glitazones - EM consulte
Annales d'Endocrinologie - Vol. 66 - N° 2-C2 - p. 190-0 - Rein et glitazones - EM consulte.
#91. Glitazones - thiazolidinediones - Esculape
Glitazones - thiazolidinediones. Avandia ® (rosiglitazone), Actos ® (pioglitazone) IL EST URGENT D'ATTENDRE.... 09/2002 - MAJ 03/2003 - 03/2005 - 03/2007 ...
#92. Pharmacological Differences of Glitazones - CORE
Both glitazones act as ligands for the nuclear hormone receptor peroxisome proliferator-activated receptor (PPAR) and regulate its transcriptional activity. On ...
#93. Trends in Drug Research III - 第 69 頁 - Google 圖書結果
The glitazones were originally derived from the fibrate clofibrate, which was noted to have weak antihyperglycemic activity in rodents.
#94. Less common drugs for type 2 diabetes glucose control
meglitinides such as nateglinide (starlix; amaryl; Xenical; glitazones. Meglitinides. Meglitinides help the pancreas make more insulin. An example of a ...
#95. Gliptins and glitazones associated with decreased risk of HF ...
Diabetes drugs included glitazones (4.5%), gliptins (6.9%), metformin (54.4%), sulphonylureas (28.7%), insulin (4.2%) and others (2.6%), as ...
#96. Understanding Type 2 Diabetes: Fewer Highs, Fewer Lows, ...
Thiazolidinediones (also known as 'glitazones' or TZDs) were introduced to diabetes care over a decade ago, with much fanfare and great expectations.
#97. 「glitazones中文」+1 胰島素增敏劑 - 藥師家
「glitazones中文」+1。Thiazolidinediones(或稱glitazones)族員包括:troglitazone、rosiglitazone與pioglitazone。在相當的治療劑量㆘,㆔者均可比安慰劑組發揮㆘.
#98. Women's Vascular Health - 第 275 頁 - Google 圖書結果
women with PCOS have now been published, including recent placebo-controlled reports.70–76 The totality of data suggests that effects of glitazones on ...
#99. Glitazon - DocCheck Flexikon
Glitazon. Synonym: Thiazolidindione, Insulin-Sensitizer Englisch: glitazones. 1 Definition. Glitazone sind zur Behandlung des Diabetes mellitus Typ 2 ...
glitazones 在 Pioglitazone, Rosiglitazone, and Troglitazone 的推薦與評價
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